A case of gunshot wound to the head is presented, in which the patient made a satisfactory recovery after a prolonged period of elevated intracranial pressure and increased cerebral extraction of oxygen. Even though cerebral extraction of oxygen was increased in the most acute phase, the arteriojugular lactate difference was never abnormally decreased (ischemic). This finding indicated that, in this patient, increased cerebral extraction of oxygen was not sufficient to result in global cerebral ischemia (increased cerebral lactate production). To our knowledge, this is the first report on frequent serial assessment of cerebral extraction of oxygen and lactate production in severe penetrating head injury.
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http://dx.doi.org/10.1097/00005373-199603000-00021 | DOI Listing |
Med Biol Eng Comput
January 2025
School of Control Science and Engineering, Tiangong University, Tianjin, 300387, China.
With the advancement of artificial intelligence technology, more and more effective methods are being used to identify and classify Electroencephalography (EEG) signals to address challenges in healthcare and brain-computer interface fields. The applications and major achievements of Graph Convolution Network (GCN) techniques in EEG signal analysis are reviewed in this paper. Through an exhaustive search of the published literature, a module-by-module discussion is carried out for the first time to address the current research status of GCN.
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January 2025
Departamento de Psicología, Universidad Iberoamericana Ciudad de México.
Medications known as 'cognitive enhancers' are increasingly being consumed off-label by healthy people, raising concerns about their safety. The aim of our study was to profile behavioral performance upon oral administration of methylphenidate (2.5 mg/kg) and modafinil (64 mg/kg) - two popular cognitive enhancers - and upon their discontinuation.
View Article and Find Full Text PDFmSphere
January 2025
WOAH Reference Laboratory for CWD, Foreign Animal Disease Division, Animal and Plant Quarantine Agency, Gimcheon, South Korea.
Chronic wasting disease (CWD) is a highly contagious prion disease occurring in free-ranging and farmed cervids. CWD continues to spread uncontrolled across North America, and cases continue to be detected almost every year in the Republic of Korea. CWD-infected animals contaminate the soil by releasing infectious prions through their excreta, and shed prions accumulate and remain infectious in the soil for years.
View Article and Find Full Text PDFStroke
January 2025
Department of Neurology, College of Medicine, University of Florida, Gainesville (M.F., A.S., T.J.P., A.K.).
Background: Mobile stroke units, also sometimes called Mobile Stroke Treatment Units (MSTUs) are changing the paradigm of acute stroke care and are considered to be an extension of the time is brain concept. Of the <20 active Mobile Stroke Programs in the United States, most are rooted in urban settings. In July 2023, the first MSTU in Florida was launched in Alachua County, implementing a unique and innovative rendezvous process with rural emergency medical services (EMS).
View Article and Find Full Text PDFBiomed Rep
March 2025
Department of Physical Therapy, Faculty of Health Sciences, Kyoto Tachibana University, Kyoto 607-8175, Japan.
In age-related peripheral neurodegeneration, changes in the promotion or inhibition of endoplasmic reticulum (ER) stress response related to the ubiquitin-proteasome degradation system (UPS), autophagy and apoptosis signaling factors during aging remain unclear. In the present study, the expression of ER stress response signaling-related protein factors was examined in tibial nerves during aging in rats. Tibial nerves were extracted from continuously housed rats at 20, 50, 70, 90 and 105 weeks of age.
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