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Research on the network structure and gender/age differences of psychological safety among urban residents: network analysis based on a large sample.
BMC Psychol
January 2025
School of Economics and Management, China University of Geosciences (Beijing), Beijing, China.
Background: Psychological safety as the key to mental health, not only affects individual happiness and quality of life but also relates to social stability and harmony. However, psychological safety is complex and multidimensional, with unclear internal structures and influencing factors and insufficient research on gender and age differences. Urban residents are living in an environment characterized by fast-paced, high-pressure, multicultural integration, and complex social relationships.
View Article and Find Full Text PDFInfluence of religion and spirituality on head and neck cancer patients and their caregivers: a protocol for a scoping review.
Syst Rev
January 2025
Preventive Oral Health Unit, National Dental Hospital (Teaching) Sri Lanka, Ward Place, Colombo 7, Sri Lanka.
Introduction: Head and neck cancers (HNC) are devastating, thus imposing a negative impact on the appearance of an individual as well as vital activities such as eating, swallowing, speaking, and breathing. Therefore, HNC patients undergo distress, while their caregivers become overburdened. Religion and spirituality can be helpful for patients and their caregivers from diverse cultural backgrounds to cope with cancer.
View Article and Find Full Text PDFThe dark side of the association between internet use and older adults' subjective wellbeing: the role of subjective social class.
BMC Geriatr
January 2025
School of Geography & Planning, Sun Yat-sen University, Guangzhou, 510006, China.
Objectives: The majority of studies exploring the relationship between internet use and subjective wellbeing among older adults tend to overlook the mediating mechanisms, particularly psychological ones. Additionally, while research has concluded that internet use is significantly associated with higher levels of subjective wellbeing, it remains unclear whether these associations might become insignificant or negative under certain conditions. To address these gaps, this study investigated the association between internet use and subjective wellbeing in older adults, with a focus on the mediating role of hope and the moderating role of subjective social class.
View Article and Find Full Text PDFCharacteristics of Tylvalosin Tartrate Enteric Amorphous Pellets Prepared by Liquid Layering.
Pharm Res
January 2025
Department of Pharmaceutics Science, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Purpose: Tylvalosin Tartrate (TAT), a new-generation macrolide antibiotic, undergoes significant degradation in the stomach and in vivo rapid elimination upon oral administration, resulting in poor bioavailability. This study developed TAT enteric amorphous pellets by liquid layering (TAT/EAP-LL) with pH-sensitive and burst release characteristics, to enhance drug stability in the stomach and concentration enrichment in the duodenum.
Methods: The drug loading layer, isolation layer and enteric layer were formed on the surface of the blank core pellets.
Efficacy of innovative systemic treatments in combination with radiotherapy for bone metastases: a GEMO (the European Study Group of Bone Metastases) state of the art.
Cancer Metastasis Rev
January 2025
Département de Radiothérapie et de Physique Médicale, Centre Henri Becquerel Rouen QuantiF, LITIS EA4108 Université Rouen, Rouen, France.
The management of bone metastases (BoM) requires a multidisciplinary approach to prevent complications, necessitating updated knowledge in light of the rapid advancements in systemic treatments and surgical, interventional radiology or radiation techniques. This review aims to discuss efficacy of new systemic treatments on BoM, the benefits of radiotherapy adjunction, and the optimal methods for combining them. Preliminary evidence suggesting reduced efficacy of immune checkpoint inhibitors (ICI), and several multi-kinase inhibitors regarding BoM may encourage early use of radiotherapy (RT).
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