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[The new face of tuberculosis in the context of the tuberculosis-HIV association in Abidjan, Ivory Coast]. | LitMetric

[The new face of tuberculosis in the context of the tuberculosis-HIV association in Abidjan, Ivory Coast].

Tuber Lung Dis

Service de pneumophtisiologie, CHU de Treichville, Abidjan, Côte d'Ivoire.

Published: December 1995

This article reviews the main clinical aspects and progression of HIV-related tuberculosis in Abidjan. HIV prevalence in tuberculosis patients is high, estimated at 46.2% in 1992, with a clear predominance of HIV-1 over HIV-2. More than 61% of co-infected tuberculous patients meet the WHO's clinical definition of AIDS (the Bangui definition) at the time of diagnosis of tuberculosis. This rates falls to 46-51% when cough is excluded from the definition. On X-rays, the signs of pulmonary tuberculosis in co-infected tuberculous patients are atypical in the advanced stages of HIV infection, when extra-pulmonary localization, mainly mediastinal adenopathy, is frequent. Short-course chemotherapy consisting of 2 months' unsupervised daily treatment with rifampicin/isoniazid/pyrazinamide, followed by 4 months of a daily combination of rifampicin/isoniazid, applied in the Ivory Coast since 15 July 1985, has proved successful in HIV-associated tuberculosis, with treatment effectiveness rates of more than 90%.

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http://dx.doi.org/10.1016/0962-8479(95)90525-1DOI Listing

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