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Is enterotoxaemia in grasscutters (Thryonomys swinderianus) caused by C. perfringens toxovars? | LitMetric

Is enterotoxaemia in grasscutters (Thryonomys swinderianus) caused by C. perfringens toxovars?

Zentralbl Veterinarmed B

Section of Hygiene, University Hohenheim, Stuttgart, Germany.

Published: November 1995

AI Article Synopsis

  • In 1985, a severe disease in domesticated grasscutters in Cotonou, Benin resulted in up to 50% population loss, characterized by necrotic small intestines and unusual Peyer's plaques.
  • Researchers identified strains of C. perfringens in healthy animals, with 81.6% belonging to type C, known for causing severe enteritis in pigs.
  • The disease was eventually eradicated through a successful prophylactic vaccination program.

Article Abstract

In 1985, in a colony of domesticated grasscutters in Cotonou/Benin (West Africa), an endemic disease that caused severe losses of up to 50 percent of the population was found. The animals regularly showed a necrotic small intestine and strongly reddened and granulated (like a raspberry) Peyer's plaques of the whole small intestine protruding into the intestinal lumen; the latter has never been described in other necrotic enteriditis caused by C. perfringens. In further investigations (Schrägle and Müller, 1989), C. perfringens strains were typed and isolated from the faeces of healthy animals, and 81.6% belonging to the type C were found, a type that causes severe necrotic enteritis in pigs. Two figures show the pathologic-anatomic findings. Meanwhile, the disease was eradicated by the use of a prophylactic vaccination.

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Source
http://dx.doi.org/10.1111/j.1439-0450.1995.tb00749.xDOI Listing

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