Dithranol for psoriasis.

Lancet

Published: March 1979

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Skin conditions are a common health concern faced by patients of all ages. For thousands of years, plants have been used to treat various skin conditions, including acne, vitiligo, and psoriasis, to name a few. Today, with increasing patient preference for natural therapies, modern medicine is now more than ever incorporating age-old knowledge of herbal remedies useful in treating skin conditions into modern-day treatments.

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The Effect of Szigetvár Medicinal Water on HaCaT Cells Exposed to Dithranol.

Life (Basel)

October 2024

Department of Public Health Medicine, Medical School, University of Pécs, 7622 Pécs, Hungary.

(1) Introduction: Topical dithranol is still commonly used today as an effective treatment for psoriasis. Dithranol treatment is often supplemented with balneotherapy, which has been shown to increase effectiveness and reduce side effects. The inorganic salts (sulfhide, selenium, zinc) are usually thought to be responsible for the effect.

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Article Synopsis
  • - Psoriasis is an inflammatory skin disease treated with topical medications like steroids and vitamin D analogs; new treatments such as tapinarof and roflumilast have shown promise with their unique anti-inflammatory effects.
  • - A review of recent studies identified strong efficacy and manageable side effects for both tapinarof and roflumilast in mild-to-moderate plaque psoriasis, with tapinarof having more frequent, mild side effects, while roflumilast had less frequent but more severe adverse events.
  • - Both treatments allow for once-daily dosing which could improve patient adherence, but cost is a concern; further research is needed to compare their effectiveness, safety, and overall cost-effectiveness.
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Psoriasis (Pso) is an autoimmune inflammatory skin disease characterized by red plaques covered in silver scales. The existing treatments provide limited benefits and are associated with certain drawbacks which limit their use. Thus, there is a need to explore more options that are highly target-specific and associated with minimal side effects.

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