AI Article Synopsis
- 24 patients with severe infections received intravenous minocycline at a dosage of 100 mg every 12 hours.
- Blood levels of the drug remained within therapeutic ranges during the initial 12 hours post-injection.
- Out of 23 evaluable patients, 20 showed successful clinical and bacteriological results, while 2 had unsatisfactory outcomes, and 1 was questionable; no serious side effects were reported, though one patient experienced a fatal secondary infection possibly linked to the treatment.
Article Abstract
24 patients with severe infections were treated with intravenous minocycline 100 mg every 12 hours. Average blood levels were within therapeutic ranges during the first 12 hours after the initial dose. Determination of efficacy of therapy in 23 of the patients who were evaluable showed that clinical and bacteriological results were satisfactory in 20 patients, unsatisfactory in 2, and questionable in 1. One patient developed a fatal secondary infection which may have been related to prior therapy with minocycline. No toxicities or side-effects were observed.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
intravenous minocycline
8
clinical evaluation
4
evaluation intravenous
4
minocycline patients
4
patients severe
4
severe infections
4
infections treated
4
treated intravenous
4
minocycline 100
4
100 hours
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!