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Impact of COVID-19 on Antimicrobial Stewardship Activities in Hospitalised Children: A Scoping Review.
J Paediatr Child Health
January 2025
School of Pharmacy and Medical Sciences, Griffith University, Gold Coast, Queensland, Australia.
Aim: COVID-19 has brought unprecedented challenges to the healthcare system. The rapid spread of the virus, laboratory burn-out, exhausted staff, diagnostic uncertainty and lack of guidelines cumulatively disrupted hospital antimicrobial stewardship (AMS) programs. This scoping review evaluated how the COVID-19 pandemic has impacted the implementation of AMS, particularly within the context of clinical audits.
View Article and Find Full Text PDFBehavior change techniques in low-calorie and very low-calorie diet interventions for weight loss: A systematic review with meta-analysis.
Obes Rev
January 2025
Obesity Institute, School of Health, Leeds Beckett University, Leeds, UK.
Background: There is limited evidence and clinical guidelines on the behavior change support required for low-calorie diet programs. This systematic review aimed to establish the behavior change technique(s) (BCT) implemented in weight loss interventions (≤1200 kcal/d) and how these contribute to effectiveness.
Methods: Databases were searched from inception to April 2022.
Non-antibiotic pharmaceuticals are toxic against Escherichia coli with no evolution of cross-resistance to antibiotics.
NPJ Antimicrob Resist
April 2024
Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Antimicrobial resistance can arise in the natural environment via prolonged exposure to the effluent released by manufacturing facilities. In addition to antibiotics, pharmaceutical plants also produce non-antibiotic pharmaceuticals, both the active ingredients and other components of the formulations. The effect of these on the surrounding microbial communities is less clear.
View Article and Find Full Text PDFLow emotional contagious behavior induces PTSD susceptibility in observers and is related to the regulation of oxytocin receptor in mice.
Cogn Affect Behav Neurosci
January 2025
School of Psychology, Shandong Second Medical University, 7166# Baotong West Street, Weifang, Shandong, 261053, P. R. China.
Background: Post-traumatic stress disorder (PTSD) is a serious psychiatric disorder that occurs after an individual has witnessed or experienced a major traumatic event. Emotional contagion seems to play an important role in witnessing trauma, highlighting the importance of understanding the neurobiological consequences of psychological or emotional stress and its impact on the individual's mental health. Therefore, understanding the relationship between emotional contagion and PTSD susceptibility and the abnormal neurobiological and behavioral changes behind it could help find effective molecular treatment targets.
View Article and Find Full Text PDFTyre rubber exposure causes oxidative stress and intracellular damage in the Baltic clam (Macoma balthica).
Environ Sci Pollut Res Int
January 2025
Marine and Freshwater Solutions, Finnish Environment Institute, Latokartanonkaari 11, 00790, Helsinki, Finland.
Car tyres are considered to release a substantial amount of particles to the environment. Due to the high emission volumes and the chemical risks associated with tyre rubber, there is an urgent need to quantify their ecotoxicological effects. The effects of exposure to particles derived from end-of-life tyres were investigated on the Baltic clam (Macoma balthica), which is one of the key invertebrate species living in the soft-bottom sediments of the northern Baltic Sea.
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