Opercular malformations are rare and complex brain malformations for which only very fragmented neuropathological descriptions have been reported. They are related to an abnormal development of both sylvian fissure and frontoparietal operculum. We report a retrospective clinical and MRI study of 11 patients presenting with opercular malformations. A congenital pseudobulbar syndrome was observed in six cases, various motor disorders in seven cases, mental retardation in six cases and epilepsy in four cases. The purpose of this study is to evaluate the main features of opercular malformations in children and to try to characterise this entity on the basis of its clinical features and MRI pattern.

Download full-text PDF

Source

Publication Analysis

Top Keywords

opercular malformations
16
clinical mri
8
opercular
4
malformations clinical
4
mri features
4
features children
4
children opercular
4
malformations
4
malformations rare
4
rare complex
4

Similar Publications

Article Synopsis
  • * In a study with 66 drug-naïve first-episode schizophrenia patients, researchers found that early-onset schizophrenia had increased low-frequency brain activity in specific frontal brain regions compared to normal controls, while adult-onset showed decreased activity in some of the same areas.
  • * The findings highlight age-related differences in brain activity, particularly in the prefrontal cortex, which could inform future treatment strategies for schizophrenia, especially for those diagnosed at a younger age.
View Article and Find Full Text PDF

The prevalence of autism spectrum disorders (ASDs) differs substantially between males and females, suggesting that sex-related neurodevelopmental factors are central to ASD pathogenesis. Numerous studies have suggested that abnormal brain specialization patterns and poor regional cooperation contribute to ASD pathogenesis, but relatively little is known about the related sex differences. Therefore, this study examined sex differences in brain functional specialization and cooperation among children with ASD.

View Article and Find Full Text PDF

To investigate the differences in resting-state functional connectivity (FC) between patients with vestibular migraine (VM) and migraine without aura (MwoA) in order to infer the possible neuroimaging mechanisms of VM. Thirty VM patients admitted to the Department of Neurology of the Second Affiliated Hospital of Xuzhou Medical University from December 2019 to December 2022 were selected as the experimental group (EG) (6 males and 24 females, with mean age of 38.3 years) and 26 MwoA patients as the control group (7 males and 19 females, mean age 35.

View Article and Find Full Text PDF
Article Synopsis
  • A 9-year-old boy in Bulgaria had a rare brain issue called MOGHE, which caused him really bad seizures since he was 3 years old.
  • Doctors discovered unusual brain activity in specific areas using special scans.
  • After surgery to remove parts of his brain, he is now 18 months seizure-free and doesn't need any medication anymore!
View Article and Find Full Text PDF

Identification of insular lobe epilepsy (ILE) presents a major clinical challenge in the diagnosis and treatment of drug-resistant focal epilepsies. ILE has diverse clinical presentations due to the multifaceted functions of the insula. Surface EEG findings do not provide straightforward information to predict this deeply-situated origin of seizures; they are even misleading, masquerading as those of other focal epilepsies, such as temporal and frontal ones.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!