The response of biochemical parameters of coagulation to chemical stimulation of different amygdaloid structures has been studied. It is demonstrated that a microinjection of L-glutamate, a stimulating amino acid, into the above structures induces hypercoagulation. This gives evidence for a direct implication of the amygdala, an essential structure of the limbic system, in the mechanisms controlling central regulation of blood coagulation with probable involvement of direct amygdalospinal tracts.
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