Premature atrial stimulation was carried out in 32 patients, and for each stimulus the basic cycle (A1A1), test cycle (A1A2), and the return cycle (A2A3) were analyzed. When A2A3 was plotted as the function of A1A2, a biphasic pattern, characterized by a slope phase followed by a "plateau", was observed in 25 subjects. Sinoatrial conduction time (SACT) was calculated using the Strauss method, which assumes that in the plateau A2A3 = A1A1 + SACT. Sinus arrhythmia was also determined in order to evaluate its importance in altering the results of premature atrial stimulation: it should be pointed out that when arrhythmia was marked it was impossible to calculate sinoatrial conduction time. An inverse correlation between A1A1 and the calculated SACT and between A1A1 and A2A3/A1A1 in the plateau was also demonstrated. The reliability of SACT obtained by premature atrial stimulation is discussed in relation to the results obtained and the data found in the literature.
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Heliyon
January 2025
Department of Information Engineering, Università Politecnica delle Marche, via Brecce Bianche, Ancona, 60131, Italy.
Background: Deep-learning applications in cardiology typically perform trivial binary classification and are able to discriminate between subjects affected or not affected by a specific cardiac disease. However, this working scenario is very different from the real one, where clinicians are required to recognize the occurrence of one cardiac disease among the several possible ones, performing a multiclass classification. The present work aims to create a new interpretable deep-learning tool able to perform a multiclass classification and, thus, discriminate among several different cardiac diseases.
View Article and Find Full Text PDFOpen Heart
January 2025
Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel.
Introduction: Data on the characteristics and outcomes of pregnancy and among patients with Fontan physiology are limited. We aimed to evaluate the immediate and long-term outcomes among these patients who were followed at our centre.
Methods: We included adult patients who had undergone Fontan surgery for congenital heart disease and were pregnant between 1994 and 2021.
Heart Rhythm
January 2025
Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, The Netherlands; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address:
Background: Focal pulsed-field ablation (F-PFA) integrated in electroanatomical mapping (EAM) systems allows tailored lesion sets in patients with atrial fibrillation (AF).
Objective: To determine feasibility, safety and 6-months outcome of F-PFA for a tailored substrate-based catheter ablation (CA) approach in patients with AF and advanced atrial substrate.
Methods: Consecutive patients with AF and advanced atrial substrate treated by a F-PFA system (Cardiofocus) through contact-force sensing catheters integrated in EAM systems were prospectively enrolled.
Background: Anti-N-methyl-D-aspartic receptor encephalitis (Anti-NMDAR encephalitis) is the most prevalent form of autoimmune encephalitis in pediatric patients. Autonomic dysfunction is a frequent symptom of Anti-NMDAR encephalitis, yet it often goes unnoticed by pediatricians. Studies have indicated that pediatric patients with autonomic dysfunction exhibit a poorer prognosis compared to those without.
View Article and Find Full Text PDFBiomed Phys Eng Express
January 2025
Electronics and Communication Engineering, Rajiv Gandhi University, Rono Hills, Doimukh, ITANAGAR, Itanagar, Arunachal Pradesh, 791112, INDIA.
Accurate detection of cardiac arrhythmias is crucial for preventing premature deaths. The current study employs a dual-stage Discrete Wavelet Transform (DWT) and a median filter to eliminate noise from ECG signals. Subsequently, ECG signals are segmented, and QRS regions are extracted for further preprocessing.
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