The effect of roentgen-contrast media on the hemolytic resistance of erythrocytes in conditions of a "hypotonic shock" and on the peroxidation of the erythrocytes lipids membranes was studied. It is shown that all the contrast media potentiate the erythrocytes hemolysis, but do not affect the rate of the lipids peroxidation. Preliminary introduction of pipolphen in a therapeutic dose in a erythrocytes suspension increases the resistance of membranes to the action of the roentgen-contrast media.

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