Objective: To evaluate the clinical presentation of arterial hypertension induced by pregnancy and pre-eclampsia (AHPP) in patients exposed to prenatal biopsychosocial risk (PBPSR).
Design: A prospective double-blind study.
Setting: Primary Care. Four Health centres in Mendoza (Argentina), Cali and Popayán (Colombia) and Tegucicalpa (Honduras).
Patients: 1,076 pregnant women who were monitored from week 14 to 28 of pregnancy without there having been clinical evidence of pathology at the start.
Measurements And Main Results: 97 (9.9%) of the 1,076 pregnant women interviewed were withdrawn from the study because their records were incomplete or they had received therapy for psychosocial risk. Average age of the 979 pregnant women studied was 26.2 +/- 5.8. 339 (34.6%) were first carriers, 439 (44.9%) had a low social-economic level, 268 (27.3%) were exposed to high biopsychosocial risk and 69 (6.4%) developed AHPP. An evaluation of the patients with this condition found that 52 of these (75.3%) were exposed to high PBPSR [RR = 8.5, C.I. 95%, 4.5-15.9, p < 0.001], 22 (42.3%) displayed anxiety and/or poor family support during their pregnancy; and 30 (57.7%) were exposed only to biomedical risk factors [RR = 3.07, C.I. 95%, 1.96-4.82, p < 0.001].
Conclusions: Whenever, as part of the evaluation of prenatal risk, the biopsychosocial risk is evaluated, the possibility of identifying pregnant patients who will develop AHPP doubles.
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Cutis
November 2024
Department of Dermatology, Ministry of Health, Ankara Training and Research Hospital, Turkey.
Current evidence indicates that obesity may initiate psoriasis or worsen existing disease. Various factors contribute to the development of obesity, including eating disorders (EDs). The aim of this study was to screen for and identify factors associated with EDs in patients with psoriasis and their impact on the development of obesity in this population.
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Dementias Platform UK - University of Oxford, Oxford, United Kingdom.
Background: According to the World Health Organization, dementia is one of the leading causes of death and at least 55 million people worldwide currently have dementia. Therefore, identifying the factors that increase the risk of developing dementia, but also those that protect against it, as well as the mechanisms underlying these effects, are essential for prevention and the development of interventions.
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Alzheimers Dement
December 2024
University of California, San Diego, La Jolla, CA, USA.
Background: Black/African American women are the most at-risk demographic group for developing Alzheimer's disease and related dementias (ADRD). Unfortunately, Black Americans are underrepresented in research, accounting for just 8% of clinical trial participants in the USA. Restrictive study exclusion criteria and medical mistrust are pervasive barriers to research participation in minoritized communities and are often disregarded during the development of a research study.
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Turner Institute for Brain and Mental Health, Monash University, Melbourne, VIC, Australia.
Background: Clinical guidelines in Australia discourage disclosure of apolipoprotein E (APOE) genotypes but advances in Alzheimer's disease (AD) therapeutics will likely change this. Limited work has assessed interest in APOE disclosure in Australian adults, and it remains unclear which characteristics are associated with interest within this sample. In a large group of middle-aged adults, this study aimed to describe interest in APOE disclosure and investigate differences in demographic and clinical characteristics and AD risk perceptions among groups with varying interest in disclosure.
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