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The Efficacy Mechanism of Epigallocatechin Gallate against Pre-Eclampsia based on Network Pharmacology and Molecular Docking.
Reprod Sci
June 2022
Department of Neonatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, People's Republic of China.
Pre-eclampsia (PE), a pregnancy complication, affects 3-5% of all pregnancies worldwide and is the main cause of maternal and perinatal morbidity. However, there is no drug which can clearly slow this disease progression. Epigallocatechin gallate (EGCG), a natural compound extracted from green tea, has been found to enhance the treatment efficacy of oral nifedipine against pregnancy-induced severe PE.
View Article and Find Full Text PDFinfection in two captive Patagonian maras.
J Vet Diagn Invest
November 2019
Norwegian University of Life Sciences, Oslo, Norway (Østevik, Tysnes, Debenham).
infection was diagnosed in 2 captive Patagonian maras (). One animal developed fatal systemic toxoplasmosis and had concurrent localized bacterial and fungal infections; its daughter remained clinically healthy. Microscopic findings included acute, coagulative necrosis, lymphohistiocytic inflammatory infiltrates, and extra- and intracellular parasites in the liver, myocardium, urinary bladder, and adrenal glands of the diseased animal.
View Article and Find Full Text PDFOral Myiasis in a Patient With HIV Manifestations and Neurologic Toxoplasmosis Treated by Ivermectin.
J Craniofac Surg
September 2018
Department of Oral and Maxillofacial Surgery and Integrated Clinic, Araçatuba Dental School, UNESP, Araçatuba, Brazil.
Myiasis has been defined as a pathologic condition where dipterous larvae are lodged in mammalian hosts causing an infestation, which feeds on living or dead tissue for at least a certain period inside the host and develops itself as parasites. In humans, the most commonly affected sites are the nose, eyes, skin wounds, sinuses, lungs, ears, gut, gall bladder, vagina, nasal cavities, and rarely the mouth because the oral tissues are rarely exposed to the external environment. The etiology of oral myiasis is usually related to local factors such as poor oral hygiene, periodontal disease and labial incompetence, and systemic factors such as neurologic deficits.
View Article and Find Full Text PDFThe relationship between toxoplasmosis and different types of human tumors.
J Infect Dev Ctries
February 2018
Zagazig University, Sharkia Governorate, Egypt.
Introduction: Toxoplasma gondii is an intracellular protozoan that may disrupt the traditional cell barriers against cancer, allowing the accumulation of oncogenic mutations over time. Our research aimed to explore the relationship between T. gondii infection and tumor development.
View Article and Find Full Text PDF[Congrès de la Société de pathologie exotique : parasitoses, mycoses et cancer 18 novembre 2015, Institut Pasteur, Paris].
Bull Soc Pathol Exot
February 2016
Société de pathologie exotique, Hôpital de la Pitié Salpêtrière, Pavillon Laveran, 47/83, boulevard de l'hôpital, 75013, Paris, France.
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