Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
[Management of risks linked to the sterilization of reusable medical devices in dentistry].
Ann Pharm Fr
January 2025
Service de la pharmacie, pharmacologie et pharmacotechnie hospitalière. Hôpital militaire principal d'instruction de Tunis, Tunisia; Faculté de pharmacie de Monastir. Université de Monastir, Tunisia.
Objective: The aim of this study was to analyze the risks associated with the sterilization process for reusable medical devices (RMD) in stomatology, by applying the FMECA method, with a view to implementing the necessary corrective and preventive actions necessary to secure this process.
Methods: The study, which was descriptive, took place between June and July 2024 in the medicine and dental surgery department of our hospital and concerned the moist heat sterilization process of RMD. The study began by defining its scope and the formation of the work team, followed by the functional analysis of the process, the identification of the failure modes (FM), the definition of the rating scales, the rating of the FM and finally the calculation of the criticality index and the development of the action plan.
Optimization of in vitro propagation and virus eradication using meristem culture and thermotherapy in two geranium species Pelargonium X hortorum ('Zonal') and Pelargonium × domesticum ('Regal').
BMC Plant Biol
January 2025
Department of Plant Production and Genetic (Biotechnology), Faculty of Agriculture, Jahrom University, Jahrom, Iran.
Background: Geraniums (Pelargonium) are among the most popular flowers worldwide. Viral infection is one of the main problems of the genus Pelargonium, and the production of virus-free mother plants is necessary for large-scale geranium propagation and exchange. Meristem culture and thermotherapy are two effective procedures that have been widely adopted to produce healthy virus-free plant stocks.
View Article and Find Full Text PDFHeat stable and intrinsically sterile liquid protein formulations.
Nat Commun
December 2024
Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, USA.
Over 80% of biologic drugs, and 90% of vaccines, require temperature-controlled conditions throughout the supply chain to minimize thermal inactivation and contamination. This cold chain is costly, requires stringent oversight, and is impractical in remote environments. Here, we report chemical dispersants that non-covalently solvate proteins within fluorous liquids to alter their thermodynamic equilibrium and reduce conformational flexibility.
View Article and Find Full Text PDFThe effect of silymarin on diabetes mellitus-induced male rats reproductive impairment: Evidences for role of heat shock proteins 70 and 90.
Pol J Vet Sci
December 2024
Department of Basic sciences, Faculty of Veterinary Medicine, Tabriz medical sciences branch, Islamic Azad University, 5159115705, Tabriz, Iran.
Male fertility is adversely influenced by diabetes. The beneficial effects of antioxidant bioflavonoids in improving fertility have been reported. This study was conducted to evaluate the effects of silymarin on diabetes mellitus-induced male reproductive impairment in rats by investigating its role in Hsp70 and Hsp90 expression.
View Article and Find Full Text PDFHeat-sterilizable antibody mimics designed on the cold shock protein scaffold from hyperthermophile Thermotoga maritima.
Protein Sci
January 2025
Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan.
Antibodies and antibody mimics are extensively used in the pharmaceutical industry, where stringent safety standards are required. Implementing heat sterilization during or after the manufacturing process could help prevent contamination by viruses and bacteria. However, conventional antibodies and antibody mimics are not suitable for heat sterilization because they irreversibly denature at high temperatures.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!