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[Infant botulism: an underestimated problem. A review].
Ter Arkh
December 2024
Izhevsk State Medical Academy.
The article is devoted to a form of botulism that has been little studied in our country and is registered exclusively in infants. The fundamental difference between this form and the most common foodborne botulism is that infants become infected by ingestion of spores, followed by their germination, colonization of the intestines and production of botulinum toxin , which leads to the development of life-threatening flaccid paralysis. Taking into account the peculiarities of pathogenesis, the clinical manifestations of infant botulism have some features, which are discussed by the authors.
View Article and Find Full Text PDFSelection of Candidate Monoclonal Antibodies for Therapy of Botulinum Toxin Type A Intoxications.
Toxins (Basel)
June 2024
Laboratory of Molecular Biology, Federal Budget Institution of Science «State Research Center for Applied Microbiology and Biotechnology», Territory "Kvartal A", 24, Obolensk, u.d., 142279 Serpukhov, Moscow Region, Russia.
Botulism is one of the most serious food intoxications, manifesting as prolonged paralytic conditions. This disease is usually the result of the consumption of poor quality canned or smoked foods, so the inhabitants of many countries of the world are exposed to the risk of this kind of poisoning every year. In view of the severity of poisonings caused by botulinum neurotoxins, monoclonal antibodies (mAbs) show great promise because of their targeting action, lack of allergic reactions and serum sickness.
View Article and Find Full Text PDFSurveillance of bacterial disease in wartime Ukraine.
BMJ Mil Health
July 2024
School of Population Health, University of New South Wales, Sydney, New South Wales, Australia.
This analysis considers circulation of bacterial disease in wartime Ukraine. Anthrax, brucellosis, botulism and tularaemia are all naturally occurring in the country. The causative agents of these diseases also formed components of the biological weapons programme the Russian Federation inherited from the Soviet Union at the end of the Cold War.
View Article and Find Full Text PDFFirst cross-border outbreak of foodborne botulism in the European Union associated with the consumption of commercial dried roach ().
Front Public Health
January 2023
Consultant Laboratory for Neurotoxin-Producing Clostridia (Botulism, Tetanus), Robert Koch Institute, Berlin, Germany.
Botulism outbreaks due to commercial products are extremely rare in the European Union. Here we report on the first international outbreak of foodborne botulism caused by commercial salt-cured, dried roach (). Between November and December 2016, an outbreak of six foodborne botulism type E cases from five unrelated households was documented in Germany and Spain.
View Article and Find Full Text PDFThe article describes a clinical observation of a severe course of a sporadic case of foodborne botulism in a woman at 32 weeks gestation with a successful resolution of pregnancy by independent childbirth. No adverse effects of botulism on pregnancy, delivery, and fetal development were noted. Anti-botulinum serum was administered to the patient no earlier than 96 hours from the onset of the disease.
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