The prevalence of anti-Legionella pneumophila serogroup 1 antibodies in 777 blood donors of the Turin area was determined by the indirect immunofluorescence assay (IFA) and by the microagglutination test (MA). Low titers (IFA of 1/16 and MA of 1/8) were found in 0.3% of the subjects. A statistically significant difference was not observed by sex and by age for IFA titers, but was noted by sex for MA titers of > or = 1/4 (p < 0.05). The upper limit of normal titer was < 1/8 by IFA and < 1/4 by MA at 15% cutoff level and 1/8 by IFA and 1/4 by MA at 1% cutoff level. In conclusion, the prevalence of antibodies in the Turin area was very low; IFA titers of > or = 1/64 and MA titers of > 1/16 can be considered as presumptive of infection in a single serum specimen of a patient with pneumonia; no change in the epidemiology of the disease was observed in the recent years.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF01721236 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antimicrobial susceptibility and epidemiological types of Legionella pneumophila human isolates from Italy (1987-2020).
J Glob Antimicrob Resist
January 2025
Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy; ESCMID Study Group for Legionella Infections (ESGLI), Basel, Switzerland. Electronic address:
Background: Although antimicrobial resistance has not yet emerged as an overarching problem for Legionella pneumophila (Lp) infection, the description of clinical and environmental strains resistant to fluoroquinolones and macrolides is a cause of concern. This study aimed to investigate the antimicrobial susceptibility of Lp human isolates in Italy.
Methods: A total of 204 Lp clinical isolates were tested for sensitivity to nine antibiotics using the broth microdilution assay (BMD).
Antibiotic susceptibility situation of environmental isolates in Southern Germany.
J Water Health
December 2024
Laboklin GmbH & Co KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.
Antimicrobial resistance is an emerging problem in hospitals and long-term healthcare facilities. Early detection of susceptibility pattern changes in pathogenic bacteria can prevent treatment failures. Therefore, this study chose to investigate the antibiotic susceptibility situation of isolates from hospitals and long-term healthcare facilities in Southern Germany.
View Article and Find Full Text PDFTwo Sporadic Cases of Legionellosis Associated with the Use of Domestic Ultrasonic Humidifiers.
Microorganisms
October 2024
Legionella Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Spain.
Two sporadic cases of legionellosis occurring in consecutive years were confirmed by positive antigenuria to serogroup 1 in individuals with limited mobility who were confined to their homes. Both cases had a history of using ultrasonic humidifiers and of low exposure to other possible sources of infection. This study was conducted through an expanded epidemiological survey and home inspection.
View Article and Find Full Text PDFAnalysis of water and aerosol samples of tunnel car washes operated with recycled water for Legionella with culture, qPCR and viability-qPCR.
Sci Total Environ
December 2024
Department of Occupational and Environmental Health, Epidemiology, Bavarian Health and Food Safety Authority, Munich, Germany; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.
Due to the generation of large quantities of aerosol and the recycling of water, tunnel car washes are discussed as potential sources of legionellosis. Additionally, occupational health and safety aspects are important for tunnel car washes as they are often workplaces. A total of 17 different tunnel car washes were investigated for the presence of Legionella.
View Article and Find Full Text PDFThe Brief Case: A fatal case of in an elderly patient.
J Clin Microbiol
November 2024
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!