We have studied two tetranucleotide short tandem repeats (STRs) (VWA and human TPO) in 260 individuals from Galicia by means of polymerase chain reaction amplification followed by electrophoresis separation and silver staining. The feasibility of the analytical technique and the level of polymorphism attained by both systems (PIC = 0.764 for VWA; PIC = 0.563 for TPO) allow us to consider the two STRs as suitable and informative markers in routine population profiling studies.
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Fa Yi Xue Za Zhi
August 2024
School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China.
Objectives: To establish the identification method of tumor tissue origin based on commonly used STR typing kits.
Methods: ForenSeq DNA Signature Prep kit was used to detect the typing of 27 autosomal STR loci in 55 paired tumor tissue samples (tumor tissue paired with normal tissue of the same individual) and 75 unrelated individual whole blood samples. The genotyping data of full sibling pairs and parent-child pairs of 55 tumor tissues were simulated.
Leg Med (Tokyo)
November 2024
Grupo de Investigación en Neurociencias, Facultad de Ciencias Médicas, Universidad Nacional Autónoma de Honduras, Edificio Ciencias de la Salud, Ciudad Universitaria, Blvd. Suyapa, Tegucigalpa, M.D.C., Honduras. Electronic address:
Leg Med (Tokyo)
July 2024
Forensic DNA Section, National Forensic Service Jeju Branch, 221, Cheomdan-ro, Jeju-si, Jeju-do 63309, Republic of Korea; Department of Forensic Medicine, Seoul National University College of Medicine, 103, Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea. Electronic address:
This study aimed to estimate A-STR mutation rates in 2,317 Korean parent-child trios by examining 20 Combined DNA Index System (CODIS) core loci (D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, CSF1PO, FGA, TH01, TPOX, vWA, D1S1656, D2S441, D2S1338, D10S1248, D12S391, D19S433, and D22S1045) and three non-CODIS loci (Penta E, Penta D, and SE33). Locus-specific mutation rate estimates varied from 0.00 to 8.
View Article and Find Full Text PDFLeg Med (Tokyo)
February 2024
Laboratorio de Genética, Ciencia Forense, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, Mexico. Electronic address:
Allele frequencies and forensic parameters for 21 STR autosomal markers (CSF1PO, D10S1248, D12S391, D13S317,D16S539, D18S51, D19S433, D1S1656,D21S11, D22S1045, D2S1338, D2S441, D3S1358, D5S818, D7S820, D8S1179, FGA, SE33, TH01, TPOX and vWA) were reported in 289 unrelated individuals from Mexico City, Mexico. In addition, an interpopulation analysis was performed including other world populations. In brief, the established population database of 21 autosomal STR markers in the present work is adequate for human identification purposes.
View Article and Find Full Text PDFAnn Hum Biol
September 2022
Department of Forensic Science, Punjabi University, Patiala, India.
Background: STR (Short Tandem Repeat) markers are highly polymorphic markers, which are widely used in forensics DNA analysis and aid to ascertain unique genotype profiles of individuals and determine the genetic diversity of the given population.
Aim: In the present study, an attempt has been made to evaluate the population genetic diversity of the Ramgharia Sikh population of Punjab, India, using 21 autosomal STR loci (D3S1358, vWA, D16S539, CSF1PO, TPOX, D8S1179, D21S11, D18S51, D2S441, D19S433, TH01, FGA, D22S1045, D5S818, D13S317, D7S820, SE33, D10S1248, D1S1656, D12S391, and D2S1338) to augment the emerging forensic database related to the indigenous population of India.
Subjects And Methods: For generation of the database, 200 (blood on FTA card) samples were obtained from genetically unrelated Ramgharia Sikhs residing in the state of Punjab.
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