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Quantitative and qualitative histological evaluation of different regions of cryopreserved skin derived from red-rumped agouti for obtaining cryobanks.
Cryobiology
January 2025
Laboratory of Animal Biotechnology, Federal Rural University of Semi-Arid (UFERSA), Mossoro, RN, Brazil. Electronic address:
Skin banks are valuable tools for the maintenance of biodiversity. The red-rumped agouti is a wild rodent of ecological importance in South America because it acts as a seed disperser, and skin banks could serve as alternatives to conserve genetic variability. Nevertheless, the most suitable skin region for forming these banks must still be determined to guarantee tissue quality after cryopreservation.
View Article and Find Full Text PDF26 Years of Skin Banking in Finland.
Eur Burn J
December 2024
Helsinki Burn Centre, Department of Plastic Surgery, Helsinki University Hospital and University of Helsinki, 00029 Helsinki, Finland.
Autologous skin grafts are the gold standard for definitive wound coverage in burn care, but allograft skin grafts are essential for providing temporary coverage in cases of extensive burns. The Helsinki Skin Bank, established in 1995 at the Helsinki Burn Centre, is Finland's only licensed skin bank, serving a population of 5.5 million.
View Article and Find Full Text PDFAdvances in preparation of acellular human dermis for tissue banking and transplantation.
Cell Tissue Bank
December 2024
NHS Blood and Transplant, Tissue Services R&D, 14 Estuary Banks, Speke, Liverpool, L24 8RB, UK.
Article Synopsis
- Non-healing wounds lead to significant costs for the NHS, totaling over £5.6 billion annually, prompting the use of skin allografts for better infection protection.
- A study aimed to validate a new decellularisation method using Benzonase, a single enzyme, to remove DNA from donor skin, which could simplify the process compared to the current dual-enzyme approach.
- Results showed that both Benzonase and the existing method effectively removed DNA without significant differences in their performance, demonstrating Benzonase's non-toxicity and potential as a cost-effective alternative in wound treatment.
Microbiological analysis of donor human milk over seven years from the Hearts Milk Bank (United Kingdom).
Food Microbiol
March 2025
School of Biological Sciences and Institute for Global Food Security, Queen's University Belfast, UK. Electronic address:
When maternal milk is unavailable, donor human milk (DHM) from human milk banks (HMBs) is the optimal alternative, as recommended by the World Health Organisation. The microbiota of DHM could contain opportunistic pathogens, which means rigorous microbiological screening for DHM, prior to pasteurisation, is recommended to safeguard recipients. Here, an analysis of 6863 DHM samples from 1419 donors at the Hearts Milk Bank between 2017 and 2023 showed approximately 70.
View Article and Find Full Text PDFMethodology for Biological Sample Collection, Processing, and Storage in the Newcastle 1000 Pregnancy Cohort: Protocol for a Longitudinal, Prospective Population-Based Study in Australia.
JMIR Res Protoc
November 2024
School of Medicine and Public Health, College and Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, Australia.
Background: Research in the developmental origins of health and disease provides compelling evidence that adverse events during the first 1000 days of life from conception can impact life course health. Despite many decades of research, we still lack a complete understanding of the mechanisms underlying some of these associations. The Newcastle 1000 Study (NEW1000) is a comprehensive, prospective population-based pregnancy cohort study based in Newcastle, New South Wales, Australia, that will recruit pregnant women and their partners at 11-14 weeks' gestation, with assessments at 20, 28, and 36 weeks; birth; 6 weeks; and 6 months, in order to provide detailed data about the first 1000 days of life to investigate the developmental origins of noncommunicable diseases.
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