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Peripheral dose assessment in radiation therapy using photon beams: experimental results with optically stimulated luminescence dosimeter.
Radiol Phys Technol
January 2025
Department of Radiation Physics, Kidwai Memorial Institute of Oncology, Bangalore, India.
The estimation of peripheral dose (PD) is vital in cancer patients with long life expectancy. Assessment of PD to radiosensitive organs is important to determine the possible risk of late effects. An attempt has been made to assess the peripheral dose using optically stimulated luminescence dosimeter (OSLD) with megavoltage photon beams as a function of field size, depth, energy, and distance from the field edge.
View Article and Find Full Text PDFSABR tolerance after prostatectomy: pushing the boundaries of ultrahypofractionation.
Clin Transl Oncol
January 2025
Department of Radiation Oncology, HM Hospitales, C/Oña 10, 28050, Madrid, Spain.
Objective: To evaluate the feasibility and tolerance of ultra-hypofractionated SABR (stereotactic ablative radiation therapy) protocol following radical prostatectomy.
Patients And Methods: We included patients undergoing adjuvant or salvage SABR between April 2019 and April 2023 targeting the surgical bed and pelvic lymph nodes up to a total dose of 36.25 Gy (7.
Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges.
Pharmaceutics
January 2025
Research Centre for Life Science and Healthcare, Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute (CBI), University of Nottingham Ningbo China, Ningbo 315000, China.
Malignant growth is expected to surpass other significant causes of death as one of the top reasons for dismalness and mortality worldwide. According to a World Health Organization (WHO) study, this illness causes approximately between 9 and 10 million instances of deaths annually. Chemotherapy, radiation, and surgery are the three main methods of treating cancer.
View Article and Find Full Text PDFProton Beam Therapy for Advanced Periocular Skin Cancer: An Eye-Sparing Approach.
Cancers (Basel)
January 2025
Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Cox 308, Boston, MA 02114, USA.
The management of periocular skin malignancies presents a unique challenge. Proton beam therapy, due to its sharp dose fall-off, allows for the delivery of a tumoricidal dose to the tumor while sparing adjacent normal tissues. Thirteen patients with a median age of 76.
View Article and Find Full Text PDFFetal Safety in MRI During Pregnancy: A Comprehensive Review.
Diagnostics (Basel)
January 2025
Arrow Program for Medical Research Education, Sheba Medical Center, Tel Hashomer, Ramat Gan 52621, Israel.
As medical imaging continues to expand, concerns about the potential risks of ionizing radiation to the developing fetus have led to a preference for non-radiation-based alternatives such as ultrasonography and fetal MRI. This review examines the current evidence on the safety of MRI during pregnancy, with a focus on 3 T MRI and contrast agents, aiming to provide a comprehensive synthesis that informs clinical decision-making, ensures fetal safety and supports the safe use of all available modalities that could impact management. We conducted a comprehensive review of studies from 2000 to 2024 on MRI safety during pregnancy, focusing on 3 T MRI and gadolinium use.
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