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Outcomes of biosynthetic collagen prostheses with comparison to cryopreserved arterial homografts for bypass reconstruction in infrainguinal vascular graft infections.
Scand J Surg
March 2025
Department of Vascular Surgery, University Medical Center Regensburg, Regensburg, Germany.
Background And Aims: Managing infrainguinal vascular graft infections (VGI) in bypass reconstruction is complex. Although an autologous vein is the preferred graft material, alternative conduits are required when autologous veins are unavailable. This study aimed to compare the efficacy of cryopreserved arterial homografts and biosynthetic glutaraldehydemodifiedovine collagen grafts (Omniflow II) for the treatment of infrainguinal VGI.
View Article and Find Full Text PDFIn Vitro Skin Penetration of 5α-Reductase Inhibitors from L.f. Leaf Extracts.
Molecules
March 2025
Department of Chemistry, Faculty of Science, Naresuan University, Phitsanulok 65000, Thailand.
The leaf extract of L.f. has shown potential as a 5α-reductase inhibitor, with two bioactive markers, namely (+)-eperua-8,13-dien-15-oic acid () and (+)-eperua-7,13-dien-15-oic acid (), used for extract standardization.
View Article and Find Full Text PDFPickering Emulsion-Based Gels with Halloysite as a Stabilizer: Formulation, Mechanical Properties and In Vitro Drug Release Studies.
Molecules
February 2025
3D Printing Division, Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland.
Lidocaine is an analgesic agent frequently incorporated in topical formulations intended for application in minor surgical procedures or relieving neuropathic pain associated with numerous conditions, including post-herpetic neuralgia or diabetic peripheral neuropathy. In this study, Pickering o/w emulsions with halloysite nanotubes as a stabilizing agent and lidocaine incorporated in the internal phase were formulated with the use of the Quality by Design (QbD) approach. The selected emulsions were transformed into semisolid gels with poloxamer 407 as a thickening agent, and investigated for rheological and textural properties, indicating the mechanical features of the obtained gels.
View Article and Find Full Text PDFHF-Ultrasonography to Quantify Skin Atrophy in Patients with Inflammatory Rheumatic Diseases Treated with Courses of Glucocorticoids.
Diagnostics (Basel)
March 2025
Department of Rheumatology and Clinical Immunology, Asklepios Medical Center Bad Abbach, 93077 Bad Abbach, Germany.
: Prolonged courses of glucocorticoids (GCs) for patients suffering from inflammatory rheumatic diseases (IRDs) are associated with adverse effects. High-frequency ultrasonography (HFUS) has been utilized to quantify skin changes during short-term topical GC treatment. We aimed to quantify skin atrophy in IRD patients treated systemically with prolonged courses of GCs.
View Article and Find Full Text PDFCerebral asymmetry: Historical introduction.
Handb Clin Neurol
March 2025
Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. Electronic address:
Cortical localization and hemispheric asymmetry of function are key concepts for analyzing the relationship between the brain, mind, and behavior in clinical neurology, neuropsychology, cognitive neuroscience, and modern philosophy. This chapter presents the history of asymmetries in the human central nervous system within the context of right-left asymmetries of bodily structure, as can be detected in individuals of virtually all living species. It has been known since antiquity that behavioral deficits on one side of the body could be caused by brain lesions on the opposite side.
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