The case of idiopathic orthostatic hypotension (Bradbury-Eggleston syndrome) which gradually arose in 70-years-old women was described. The clinical pattern of syndrome included pronounced orthostatic hypotension, fixed constant rare pulse (46-56 per minutes), independent of the changes in body position together with hypohidrosis and constipation. Autonomic nervous system investigation carried out with the help of the cardiovascular tests, spectral analysis of heart rhythm as well as sympathetic skin potential revealed expressed disturbances in autonomic functions of cardiovascular and sudomotor systems. Peculiarity of the case was the development of disease on the background of drug-compensated hypothyreosis which was not however the cause of progressive autonomic disorders in patient.

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