The multiple chemical sensitivity syndrome (MCS) is a novel constellation of symptoms in environmental medicine that has been extensively described and commented on in the USA. The main features of this syndrome are: multiple symptoms in different organ systems triggered by a variety of chemical substances, with relapses and exacerbations under certain precipitating circumstances at very low levels which do not cause any reactions in the population at large. There are no lab markers or specific investigative findings. This paper describes the historical development of the term MCS, its diagnostic criteria and pathophysiological aspects using 10 patient histories from our hospital.
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