Recurrent meningococcal septicaemia and properdin deficiency.

J Infect

Department of Infectious Diseases and Tropical Medicine, (Monsall Unit) North Manchester General Hospital, Crumpsall, U.K.

Published: July 1995

A 32-year-old male presented with two episodes of meningococcal septicaemia, each of which was caused by a different serogroup of Neisseria meningitidis. Examination of the alternative pathway of complement revealed the rare X-linked disorder properdin deficiency (PD). Meningococcal Infection in complement deficiency states is discussed and the unusual features of this case are highlighted.

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http://dx.doi.org/10.1016/s0163-4453(95)91550-8DOI Listing

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