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The dual role of thymic neurohypophysial-related self peptides in T cell selection. Physiological and pharmacological implications.
Ann N Y Acad Sci
July 1993
Department of Endocrinology, Institute of Pathology B23, University of Liège-Sart Tilman, Belgium.
Thymic neurohypophysial-related peptides and T cell selection.
Regul Pept
April 1993
Institute of Pathology B23, University of Liège-Sart Tilman, Belgium.
[The central role of the thymus in the education of T cells to neuroendocrine principles].
Verh K Acad Geneeskd Belg
May 1993
Centre Hospitalier Universitaire de Liège, Domaine universitaire du Sart-Tilman.
The thymus, the lymphoid organ responsible for the induction of central T cell self-tolerance, is the site of expression of peptides belonging to the neurohypophysial peptide family. The classical model of neurosecretion established by the Scharrers for the hypothalamo-neurohypophysial axis however cannot be applied to characterize the secretory pathways of neurohypophysial-related peptides in the thymic epithelial component. The novel model of cell-to-cell cryptocrine signalling has recently been proposed by J.
View Article and Find Full Text PDFBiosynthesis and paracrine/cryptocrine actions of 'self' neurohypophysial-related peptides in the thymus.
Mol Cell Endocrinol
April 1991
Department of Endocrinology, University Hospital of Sart Tilman B23, Liège, Belgium.
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