The rheumatoid joint is hypoxic. The loss of the physiologic defense mechanism, reflex muscle inhibition, allows the generation of high intraarticular pressures, particularly during exercise. Hypoxia alters the biochemistry of the synovium and encourages the production of reactive oxygen species (ROS) on reperfusion of blood. In excess, ROS damage tissues, and the products of oxidative damage are detectable in rheumatoid synovial fluid. In addition to damaging proteins, carbohydrates and lipids, cellular and structural damage also occurs.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Learning (Not) to Know: Examining How White Ignorance Manifests and Functions in White Adolescents' Racial Identity Narratives.
Child Dev
January 2025
Department of Psychology, Northwestern University, Evanston, Illinois, USA.
In critical approaches to the study of whiteness, white ignorance refers to systematic and intentional ways of (not) knowing that function to perpetuate racism. The current critical qualitative analysis examines how white ignorance surfaces in the racial identity narratives of white adolescents (N = 69, M = 15.91, SD = 0.
View Article and Find Full Text PDFGrowing microbiology literacy through interdisciplinary approaches to food fermentations and an Indigenous peoples' rights framework.
J Microbiol Biol Educ
January 2025
Department of Food Science and Technology, University of California, Davis, California, USA.
New approaches to microbiology education are needed to ensure equitable representation in microbiology and to build literacy in microbiology and science broadly. To address this goal, we developed a course held at the collegiate level that uniquely integrated microbiology, Indigenous studies, science and technology studies, and arts and performance. The course participants included students in 12 majors across science, engineering, humanities, and arts.
View Article and Find Full Text PDFA brain-computer interface system for lower-limb exoskeletons based on motor imagery and stacked ensemble approach.
Rev Sci Instrum
January 2025
Shenyang Bluewisdom Technology Co., Ltd., Shenyang, Liaoning Province 110623, China.
Existing lower limb exoskeletons (LLEs) have demonstrated a lack of sufficient patient involvement during rehabilitation training. To address this issue and better incorporate the patient's motion intentions, this paper proposes an online brain-computer interface (BCI) system for LLE based motor imagery and stacked ensemble. The establishment of this online BCI system enables a comprehensive closed-loop control process, which includes the collection and decoding of brain signals, robotic control, and real-time feedback mechanisms.
View Article and Find Full Text PDF[Quantification of Facial Asymmetry : A Comprehensive Review of Methods and Applications].
Orthod Fr
January 2025
Laboratoire Forme et Croissance du Crâne, Institut Imagine, 24 boulevard du Montparnasse, 75015 Paris, France
Introduction: Facial asymmetry, present in all human faces at varying degrees, plays a critical role in clinical fields such as orthodontics, orthognathic and plastic surgeries, and craniofacial reconstruction. Accurate quantification of facial asymmetry is essential for diagnosis, treatment planning, and post-surgical evaluation.
Material And Methods: This article examines contemporary methods for quantifying facial asymmetry, including two-dimensional (2D) and three-dimensional (3D) landmark-based approaches, surface curvature analysis, and advanced image-based techniques.
Action of the Euclidean versus projective group on an agent's internal space in curiosity driven exploration.
Biol Cybern
January 2025
CIAMS, Université Paris-Saclay, Orsay & Université d'Orléans, Orléans, France.
According to the Projective Consciousness Model (PCM), in human spatial awareness, 3-dimensional projective geometry structures information integration and action planning through perspective taking within an internal representation space. The way different perspectives are related to and transform a world model defines a specific perception and imagination scheme. In mathematics, such a collection of transformations corresponds to a 'group', whose 'actions' characterize the geometry of a space.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!