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Maternal caffeine intake during pregnancy and the risk of childhood asthma by 10 years of age-Evidence from The Generation XXI birth cohort study.
Pediatr Allergy Immunol
January 2025
EPIUnit-Institute of Public Health, University of Porto, Porto, Portugal.
Background: We aimed to investigate the association between maternal caffeine intake during pregnancy and asthma in children by 10 years of age.
Methods: We considered 5585 mother-child pairs enrolled in a population-based birth cohort. Consumption of regular and decaffeinated coffee, black and green tea, and cola beverages before and during pregnancy was obtained through face-to-face interviews within 72 h after giving birth, and total caffeine intake (mg/day) was estimated.
Exploring caffeine as a disruptor of membrane integrity and genomic stability in Staphylococcus aureus: functional and in silico analysis.
Arch Microbiol
January 2025
School of Basic and Applied Sciences, Department of Biological Sciences, Dayananda Sagar University, Innovation Campus, Kudlu Gate, Hosur Rd, Bengaluru, 560 068, India.
To explore the mechanistic underpinnings of caffeine as a potent antibacterial against Staphylococcus aureus ATCC 25923 via in vitro functional assays, whole-genome sequencing, and in silico docking studies. In vitro studies established that caffeine's minimum inhibitory concentration (MIC) against S. aureus ATCC 25923 is 0.
View Article and Find Full Text PDFTailored recovery of antioxidant fractions enriched in caffeine and phenolic compounds from coffee pulp using ethanol-modified supercritical carbon dioxide.
Food Res Int
January 2025
Department of Agricultural Chemistry and Food Science, Faculty of Science, C/ Francisco Tomás y Valiente, 7, Universidad Autónoma de Madrid, 28049 Madrid, Spain; Department of Production and Characterization of Novel Foods, Institute of Food Science Research, CIAL (UAM-CSIC), 28049 Madrid, Spain. Electronic address:
Coffee pulp (CP) is the by-product of coffee processing that urgently needs to be revalorized using sustainable technologies. This work applied a design of experiment (DoE) for modeling the extraction of bioactive compounds from CP using supercritical carbon dioxide (sc-CO) with ethanol as a co-solvent under variable conditions (temperature, pressure, and ethanol percentage). Considering extraction efficiency (per unit of CP) and extraction selectivity (per unit of extract), results showed that ethanol percentage significantly enhanced the efficiency of total phenolic content, as well as the selectivity of chlorogenic acid and protocatechuic acid (p < 0.
View Article and Find Full Text PDFEvaluation of sources, spatial and temporal distribution, ecological and health risk associated with CAF (Caffeine) and DEET (N, N-diethyl-meta-toluamide) contamination in the urban groundwater parts of Vellore city, Tamilnadu, India.
Environ Geochem Health
January 2025
School of Civil Engineering, Vellore Institute of Technology, Tamil Nadu, Vellore, 632014, India.
Urban environments are heavily influenced by various activities, leading to contamination of water sources by emerging contaminants (ECs). Among these, caffeine (CAF) and N, N-diethyl-meta-toluamide (DEET) are notable ECs frequently found in domestic sewage due to human activities. Despite extensive research on emerging contaminants, limited studies have focused on the seasonal variations, human health and ecological risks of CAF and DEET in urban groundwater, particularly in Indian cities.
View Article and Find Full Text PDFAtmospheric Pressure Mass Spectrometry Imaging Using Electrospray-Assisted Laser Desorption/Ionization with Gas Transportation through a Heated Tube and Minimal Sample Preparation.
Mass Spectrom (Tokyo)
December 2024
Graduate School of Engineering, Osaka University, A1/A14, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Mass spectrometry (MS) is a valuable tool that enables label-free analysis and the ability to measure multiple molecules. The atmospheric pressure MS imaging (MSI) method usually requires tedious sample preparation. A simple ionization method with minimal sample preparation is needed for high-throughput analysis.
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