2-Acetamido-3,4,6-tri-O-benzoyl-2-deoxy-alpha-D-mannopyranosyl hydrogen phosphonate was synthesised and used for the first syntheses of glycosyl phosphosugars containing N-acetylmannosamine residue. The phosphodiesters prepared include ManNAc(alpha)-P-6Man(alpha)Me, an analogue of the fragment of some lysosomal glycoproteins, and ManNAc(alpha)-P-6ManNAc(alpha)Np, a derivative of the fragment of the capsular antigen from Neisseria meningitidis A.
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