[The patterns in the functioning of the hypothalamo-hypophyseal-adrenal cortex system].

Main principles of functioning of the hypothalamus-hypophysis-adrenal cortex system (HHACS) in conditions of stress activation and rhythmic excitation and inhibition are characterized. Interrelations between input signals, disturbing the HHACS, and output parameters of its activity, are described. The role of central and peripheral parts of HHACS in the realization of the principles of its functioning is analyzed. The concept on the significance of HHACS construction as a system of three hormonal links is considered. The dependence of adaptive capacities of the body on the HHACS state is characterized. Recently discovered features of corticosteroid hormones as agents increasing adaptive resources--the antinociceptive and the antiulcer actions--are discussed.