Fingertip and venous blood lactate concentrations were determined pre-exercise and after 4-min bouts of treadmill running at 2.69, 3.13, 3.58 and 4.03 m s-1 in 14 normal healthy volunteers. A 1-min rest period intervened each exercise period, and was used for the simultaneous sampling of fingertip and venous blood. Compared to pre-exercise, fingertip and venous blood lactate (BLa) concentrations increased significantly (P < 0.05) in a progressive pattern with increasing exercise intensity. Fingertip BLa concentrations were significantly higher (P < 0.05) than venous blood prior to exercise and in response to all four running speeds. Treadmill speed, heart rate and oxygen consumption were significantly lower (P < 0.05) at a BLa concentration of 4 mM when estimated from fingertip blood as compared with venous blood. These results indicate that differences between fingertip and venous blood exist during treadmill exercise and should be considered when lactate determination is employed as a criterion to evaluate and predict performance and when used as a training guide to standardize exercise intensity.
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http://dx.doi.org/10.1080/02640419308729977 | DOI Listing |
Arch Dermatol Res
January 2025
Department of Dermatology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Vitiligo is considered as depigmenting skin disorder where patches of skin losing their pigment. Lipocalin-2 (LCN2) is one of the Inflammatory adipokines that has a potential role in skin disorders and other inflammatory diseases as well. To measure the concentration level of LCN2 in vitiligo patients compared to healthy controls and to investigate its relation to disease activity and other clinical data to evaluate its role in the pathogenesis of the disease.
View Article and Find Full Text PDFRev Gastroenterol Peru
January 2025
Centro de Gastroenterología, Bogotá, Colombia; Gastroenterología y endoscopia digestiva, Universidad Nacional de Colombia, Bogotá, Colombia; Gastroenterología, Hospital Universitario Nacional de Colombia, Bogotá, Colombia.
In this article, we present an exceptionally rare and challenging clinical case. It concerns a 65-year-old woman who, while eating, accidentally ingested a thorn. This foreign body, after being swallowed, migrated from the proximal esophagus, until it penetrated the left internal jugular vein.
View Article and Find Full Text PDFEur J Haematol
January 2025
Venous Thromboembolism Unit, Internal Medicine Department, General University Hospital Gregorio Marañón, Madrid, Spain.
Introduction: Anticoagulant therapy is critical for venous thromboembolism (VTE) management, though bleeding remains a major concern, ranging from mild to fatal events. This study aimed to assess the predictive value of cytokines for major bleeding in patients with acute pulmonary embolism (PE).
Methods: In this prospective, observational study, patients aged ≥ 18 years with acute PE were enrolled from April 2021 to September 2022 and followed for 30 days.
Zhongguo Dang Dai Er Ke Za Zhi
January 2025
Department of Pediatrics, Third People's Hospital of Longgang District of Shenzhen, Shenzhen, Guangdong 518020, China.
Objectives: To explore the role of berberine (BBR) in ameliorating coronary endothelial cell injury in Kawasaki disease (KD) by regulating the complement and coagulation cascade.
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BMC Pediatr
January 2025
Department of Pediatrics, Tongde Hospital of Zhejiang Province, No. 234, Gucui Road, Hangzhou, 310000, China.
Background: Childhood pneumonia (CP) is a common respiratory infectious disease in children with high morbidity and mortality. However, differential changes in miRNAs may interact with the regulation of CP. The aim of this paper was to discuss the miR-200b expression in CP and its diagnostic and prognostic value.
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