[Amidation of proteins and peptides with carboxypeptidase Y]. | LitMetric

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[Amidation of proteins and peptides with carboxypeptidase Y]. | LitMetric

[Amidation of proteins and peptides with carboxypeptidase Y].

T N Amosova A A Popov N E Kudriavtseva Iu V Kapitannikov L D Rumi V K Antonov

Bioorg Khim

Published: April 1993

The native and modified carboxypeptidase Y-catalyzed reaction of acyl transfer of acylamino acid and peptide residues from the corresponding esters to ammonia was studied. Use of the modified carboxypeptidase Y increased the yield of the resulting product. Calcitonin-Leu was transformed into human calcitonin.

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