Alanine release by rat diaphragm muscle in vitro is stimulated by glutamate, valine, leucine and glucose. The stimulation by glutamate and valine (but not leucine) is inhibited by 3-mercaptopicolinate. These results suggest a metabolic route involving phosphoenolpyruvate carboxykinase which directs amino acid carbon skeletons towards pyruvate synthesis for alanine formation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1164613 | PMC |
| http://dx.doi.org/10.1042/bj1620399 | DOI Listing |
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