Borrelia burgdorferi B31 cells lacking all linear plasmids or all but the 49-kb linear plasmid expressed the otherwise silent gene for the outer membrane protein OspC. In the first demonstration of a function for a circular plasmid of Borrelia spp., ospC was located on a 27-kb circular plasmid of B31.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC280820PMC
http://dx.doi.org/10.1128/iai.61.5.2192-2195.1993DOI Listing

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