The value of magnetic resonance (MR) to establish the diagnosis of multiple sclerosis (MS) is well known. This study was undertaken to compare MR imaging of the brain of MS patients at high (1.5T) and mid (0.5T) field strength. 25 patients with MS underwent two consecutive MR studies within one hour, each consisting of axial proton density and T2-weighted spin-echo images. Lesions in the supratentorial white matter and corpus callosum and those in the brain stem and cerebellum were separately counted. At 1.5T significantly more lesions were seen than at 0.5T (p < 0.05). Although T2-weighted images at 1.5T added significant information compared to images obtained at 0.5T, in none of our 25 patients the diagnosis was missed at 0.5T. However, at 1.5T dissemination in space was better demonstrated, suggesting MR scanning with high field-units to be favourable in patients with clinically suspected MS.
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http://dx.doi.org/10.1055/s-2008-1032665 | DOI Listing |
Sci Rep
January 2025
Guizhou Mining Safety Science Research Institute Co., Ltd, Guiyang, 550025, China.
To enhance the safety of coal mining operations and improve the efficiency of gas extraction, hydraulic flushing technology has been widely used in low permeability coal seams. This study aims to investigate the mechanism of hydraulic flushing by conducting experiments focusing on four aspects: sample strength, punching pressure, punching position and vibration direction. The results show that an increase in hydraulic flushing pressure leads to a deeper impact groove, whereas higher sample strength results in a shallower groove.
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January 2025
Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing, 100081, China.
Loess is extensively developed on both sides of the Longwu River, a tributary of the Yellow River, Tongren County, Qinghai Province. The engineering geological characteristics are complex, and landslide disasters are highly developed. Based on field geological surveys and physical property analysis of the loess in this area, this study analyzes the influence of water content, consolidation pressure, and soil disturbance on the dynamic characteristics of loess using GDS dynamic triaxial tests.
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January 2025
School of Electrical and Electronic Engineering, Hanoi University of Science and Technology, Hanoi, Viet Nam. Electronic address:
In the field of medical science, skin segmentation has gained significant importance, particularly in dermatology and skin cancer research. This domain demands high precision in distinguishing critical regions (such as lesions or moles) from healthy skin in medical images. With growing technological advancements, deep learning models have emerged as indispensable tools in addressing these challenges.
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January 2025
Bioinformatics and Computational Biology Program, Iowa State University, Ames, IA 50011, USA; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA. Electronic address:
There is an ever-increasing need for accurate and efficient methods to identify protein homologs. Traditionally, sequence similarity-based methods have dominated protein homolog identification for function identification, but these struggle when the sequence identity between the pairs is low. Recently, transformer architecture-based deep learning methods have achieved breakthrough performances in many fields.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Tianjin Key Laboratory of Pulp and Paper, Tianjin University of Science and Technology, Tianjin 300457, China. Electronic address:
A multifunctional hydrogel with outstanding mechanical properties and excellent ionic conductivity holds immense potential for applications in various fields, such as healthcare monitoring, and various devices, such as wearable devices and flexible electronics. However, developing hydrogels that combine high mechanical strength with efficient electrical conductivity remains a considerable challenge. Herein, an ion-conductive hydrogel with excellent mechanical properties and ionic conductivity is successfully created.
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