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Background: Drivers of COVID-19 severity are multifactorial and include multidimensional and potentially interacting factors encompassing viral determinants and host-related factors (i.e., demographics, pre-existing conditions and/or genetics), thus complicating the prediction of clinical outcomes for different severe acute respiratory syndrome coronavirus (SARS-CoV-2) variants.
View Article and Find Full Text PDFAdvancements and Perspectives in Biodegradable Polyester Elastomers: Toward Sustainable and High-Performance Materials.
Int J Mol Sci
January 2025
Academy for Engineering and Technology, Yiwu Research Institute, Zhuhai Fudan Innovation Institute, Fudan University, Shanghai 200433, China.
While the traditional rubber industry faces the severe pressure of environmental pollution and carbon emissions, bio-based and biodegradable elastomers have become a hot topic in the field and drawn intensive research interest. Inspired by polyester resin, incorporating polyol or polycarboxylic acid as a branching unit into aliphatic polyester and/or introducing a monomer with a C=C bond to provide open-bond cross-linking in the fashion of common vulcanization to form three-dimensional network structures are two mainstream strategies for designing biodegradable polyester elastomers (BPEs). Both methods encounter more or fewer problems, such as poor mechanical and thermal properties due to the easy hydrolysis of the ester bond and space hinderance, or the potential harm of the remaining degraded small molecules with olefin bonds.
View Article and Find Full Text PDFHealth provider perspectives on establishing service linkages for treatment and follow-up from an Australian, web-based STI testing service: a qualitative study.
Sex Health
January 2025
Melbourne School of Population and Global Health, University of Melbourne, Parkville, Vic, Australia.
Background Web-based, testing for sexually transmitted infections (STI) is becoming increasingly available. However, treatment pathways from web-based services are often not well-coordinated, contributing to treatment delays and access gaps. This study investigated clinician perspectives on building service linkages with a new, web-based, STI testing service in Victoria, Australia.
View Article and Find Full Text PDFSleep, coparenting, and parenting among mothers and fathers prior to kindergarten transition.
J Fam Psychol
January 2025
Department of Human Development and Family Studies, Pennsylvania State University.
The identification of family-level and modifiable factors that are influential determinants of parenting is of critical importance. The present study of mothers and fathers investigated within- and across-parent linkages between sleep duration and variability, the coparenting relationship, and parenting quality, as well as the moderating effect of coparenting in a sample of families with children making the transition to kindergarten using a family systems perspective. Mothers and fathers from 225 families participated in the late summer before their child started kindergarten.
View Article and Find Full Text PDFCorrelation between the structures of natural polysaccharides and their properties in regulating gut microbiota: Current understanding and beyond.
Carbohydr Polym
March 2025
School of Chinese Medicine, Hong Kong Baptist University, Hong Kong. Electronic address:
Natural polysaccharides have complex structural properties and a wide range of health-promoting effects. Accumulating evidence suggests that the effects are significantly mediated through fermentation by gut microbiota. In recent years, the relationship between the structures of natural polysaccharides and their properties in regulating gut microbiota has garnered significant research attention as researchers attempt to precisely understand the role of gut microbiota in the bioactivities of natural polysaccharides.
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