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Antibiotic Resistance Profile of Enterovirulent Isolates Harboring Broad-Spectrum Beta-Lactamase Genes in Cancer Patients at the Laquintinie Hospital in Douala, Littoral Region, Cameroon.
Int J Microbiol
January 2025
Department of Biochemistry, Faculty of Science, Université de Dschang, Dschang, Cameroon.
Cases of antibiotic-resistant () infections are becoming increasingly frequent and represent a major threat to our ability to treat cancer patients. The emergence of antimicrobial resistance threatens the treatment of infections. In this study, the antimicrobial profiles, virulent genes, and the frequency of extended-spectrum beta-lactamase (ESBL) gene carriage in fecal isolates from cancer patients at the Laquintinie Hospital in Douala (Cameroon) were determined.
View Article and Find Full Text PDFDetection of bla, bla, bla, and bla genes of antibiotic resistance in diarrheagenic E. coli causing enteric infection in hypertensive patients at Laquintinie Hospital, Littoral Region of Cameroon.
J Infect Public Health
January 2025
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon. Electronic address:
Article Synopsis
- Pathogenic Escherichia coli is a leading cause of diarrhea globally, and this study investigates how virulence genes and antibiotic resistance differ in hypertensive versus non-hypertensive patients.* -
- Researchers analyzed 518 fecal samples from patients in Douala, discovering that certain strains like enteropathogenic E. coli (EPEC) were more common in hypertensive individuals, while enteroaggregative E. coli (EAEC) predominated in non-hypertensives.* -
- The study found high resistance rates of E. coli to antibiotics, especially amoxicillin and sulfamethoxazole-trimethoprim, with a significant prevalence of extended-spectrum β-lactamase-producing strains (
Antibacterial activity against enterovirulent Escherichia coli strains from Bacillus amyloliquefaciens B31 and Bacillus subtilis subsp. subtilis C4: MALDI-TOF MS profiling and MALDI TOF/TOF MS structural analysis on lipopeptides mixtures.
J Mass Spectrom
December 2022
Instituto de Investigaciones para la Industria Química (INIQUI), CONICET, Universidad Nacional de Salta, Av. Bolivia 5150, Salta, 4400, Argentina.
In this work, two Bacillus strains isolated from honey (Bacillus subtilis subsp. subtilis C4; access code HQ828992) and from a waste of an artisanal tannery (Bacillus amyloliquefaciens B31; access code KP893752) were evaluated in order to determine their antibacterial activity against five enteropathogenic Escherichia coli strains. The number of viable cultivable cells of the different strains of E.
View Article and Find Full Text PDFProfiling Virulence and Antimicrobial Resistance Markers of Enterovirulent from Fecal Isolates of Adult Patients with Enteric Infections in West Cameroon.
Osong Public Health Res Perspect
August 2020
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Objectives: This study aimed to identify virulent and antimicrobial resistant genes in fecal in Mbouda, Cameroon.
Methods: A total of 599 fecal samples were collected from patients with enteric infections who were ≥ 20 years old. was isolated on the MacConkey agar and virulent genes were detected by multiplex/simplex PCR.
Multidrug resistance and multivirulence plasmids in enterotoxigenic and hybrid Shiga toxin-producing/enterotoxigenic Escherichia coli isolated from diarrheic pigs in Switzerland.
Vet J
February 2019
Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Enterovirulent Escherichia coli infections cause significant losses in the pig industry. However, information about the structures of the virulence and multidrug resistance (MDR) plasmids harboured by these strains is sparse. In this study, we used whole-genome sequencing with PacBio and Illumina platforms to analyse the molecular features of the multidrug-resistant enterotoxigenic E.
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