Pathologic correlations with magnetic resonance images of osteochondrosis lesions in canine shoulders.

Twelve shoulders in 6 dogs with clinical and radiographic evidence of osteochondrosis were examined by magnetic resonance imaging performed on a 0.5-T superconductive system. Scans were obtained with 5-mm-thick slices and 0.75-mm pixel size. Unenhanced T1-weighted spin-echo and unenhanced T2*-weighted gradient-echo images were obtained, using a high-resolution surface coil. The T1-weighted sequences were repeated after IV injection of 0.1 mmol of gadopentetate dimeglumine/kg of body weight (0.2 ml/kg). In 6 joints, histologic examination of synovia and articular cartilage was carried out. The magnetic resonance images were correlated with arthrographic, arthroscopic, and histologic findings. Magnetic resonance imaging was useful in evaluating the extent of subchondral lesions and the severity of inflammatory changes within the subchondral bone. Areas of low signal (visible subchondrally on T1-weighted images that were enhanced by administration of contrast medium) indicated active inflammatory changes within the subchondral bone. Although articular cartilage discontinuity could be detected, loose cartilage flaps could not always be reliably demonstrated. Signal inhomogeneity within the articular cartilage was presumed to correspond with zones of cartilage degeneration.