The aim of this study was to determine the extent to which variation in socioeconomic factors derived from the 1986 census could "explain" variation in standardised mortality ratio (SMR) between the 322 electoral wards and district electoral divisions (DEDs) in Dublin. Factors examined included percentage of population in the various Irish social class groupings, percentage of male unemployment, number of cars per private household and number of persons per car. Regression analysis between SMR and each of these factors individually showed a significant relationship in every case. The explanatory variables studied were all highly correlated and stepwise forward multiple regression was used to identify factors which had an independent effect. Two factors emerged as significant--percentage of persons in social classes 5 & 6 (semiskilled and unskilled) and number of cars per private household. This model explained 27.4% of the variance in SMR. We conclude that the variation of SMRs between DEDs in Dublin can partly be explained by variation in socioeconomic factors.
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Neuro Oncol
January 2025
Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Background: Central nervous system (CNS) tumors lead to cancer-related mortality in children. Genetic ancestry-associated cancer prevalence and outcomes have been studied, but is limited.
Methods: We performed genetic ancestry prediction in 1,452 pediatric patients with paired normal and tumor whole genome sequencing from the Open Pediatric Cancer (OpenPedCan) project to evaluate the influence of reported race and ethnicity and ancestry-based genetic superpopulations on tumor histology, molecular subtype, survival, and treatment.
Proc Natl Acad Sci U S A
January 2025
The Harris School of Public Policy, University of Chicago, Chicago, IL 60637.
Americans collectively hold over $1.6 trillion in student loan debt, and over the last decade millions of borrowers have defaulted on loans, with serious consequences for their financial health. In a 13-million-person field experiment with the U.
View Article and Find Full Text PDFMatern Child Health J
January 2025
Department of Economics, Pondicherry University, Puducherry, India.
Background: Out-of-pocket expenditure (OOPE) and catastrophic health expenditure (CHE) on institutional deliveries in India impose significant financial burdens, disproportionately affecting socio-economically vulnerable populations and regions despite various policy interventions.
Purpose: This study evaluates the extent of OOPE and CHE associated with institutional deliveries across Indian states and analyse regional variations using data from National Family Health Survey -5 (2019-21).
Results: The findings reveal substantial inter-state and regional disparities in mean OOPE and CHE incidence, with socioeconomic and healthcare system factors significantly influencing these outcomes.
Curr Cardiol Rep
January 2025
John Ochsner Heart and Vascular Institute, Ochsner Clinical School University of Queensland School of Medicine, New Orleans, LA, USA.
Purpose Of Review: To provide a narrative overview of trends and disparities in the cardiometabolic profiles of U.S. adults by synthesizing findings from nationally representative studies conducted between 1999 and 2020.
View Article and Find Full Text PDFCancer Causes Control
January 2025
Division of Health Policy and Management, University of California, Berkeley, Berkeley, CA, USA.
Purpose: Older Black women and women living in areas of low socioeconomic status (SES) diagnosed with cervical cancer (CC) have worse overall survival (OS). The objective was to investigate associations between OS and race/ethnicity and sociodemographic factors in younger (21-64 years) and older women (≥ 65 years) diagnosed with CC using Surveillance, Epidemiology, and End Results Program data.
Methods: This retrospective, population-based cohort study included 39,000 women ≥ 21 years diagnosed with CC diagnosed between 2006 and 2020.
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