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Strategies to prevent postoperative delirium: a comprehensive evaluation of anesthesia selection and drug intervention.
Front Psychiatry
December 2024
Department of Orthopedics, The Second Hospital of Anhui Medical University, Hefei, China.
Postoperative delirium (POD) represents a common neurological complication encountered predominantly among the elderly cohort undergoing surgical intervention for hip fractures. This phenomenon, particularly commonplace in geriatric populations with heightened preoperative risk profiles, pronounced comorbidities, and later stages of lifespan, poses complex clinical challenges. The impact of perioperative pharmacological interventions and anesthetic strategies on POD's emergence cannot be understated, as it may profoundly affect the length of hospital stays, rehabilitation milestones, and the overall mortality hazard.
View Article and Find Full Text PDFAnnual Banned-Substance Review 17th Edition-Analytical Approaches in Human Sports Drug Testing 2023/2024.
Drug Test Anal
December 2024
Center for Preventive Doping Research, Institute of Biochemistry, German Sport University Cologne, Cologne, Germany.
The 17th edition of the annual banned-substance review on analytical approaches in human sports drug testing is dedicated to literature published between October 2023 and September 2024. As in previous years, focus is put particularly on new or enhanced analytical options in human doping controls as well as investigations into the metabolism and elimination of compounds of interest, which represent central (while not exclusive) cornerstones of the global anti-doping mission. New information published within the past 12 months on established doping agents as well as new potentially relevant substances are reviewed and discussed in the context of the World Anti-Doping Agency's 2024 Prohibited List.
View Article and Find Full Text PDFThe COVID-19 pandemic has highlighted the critical role of mobile health applications in the management of health crises. Despite the promising outcomes of these technologies, however, their acceptance and use among physicians in the developing world such as Saudi Arabia are notably low. The study aimed to explore the factors influencing the acceptance and adoption of mobile health applications by physicians in Saudi Arabia during the COVID-19 pandemic.
View Article and Find Full Text PDFExtracellular vesicles from human adipose-derived stem cell spheroids: Characterization and therapeutic implications in diabetic wound healing.
Mater Today Bio
December 2024
Department of Surgery, National Taiwan University Hospital and College of Medicine, Taipei 100, Taiwan.
Article Synopsis
- The management of diabetic wounds is difficult, but extracellular vesicles (EVs) from human adipose-derived stem cells (hASCs) show potential for treatment despite challenges with their quantity and quality.
- A novel method using cell spheroids to culture hASCs successfully increased the yield and angiogenic properties of the EVs, leading to improved wound healing characteristics.
- In vivo tests on diabetic rats demonstrated that these enhanced EVs significantly improved collagen production, wound closure, and blood vessel formation, suggesting a promising new approach for treating diabetic wounds.
Formate and CO* Radicals Intermediated Atmospheric CO Conversion over Co-Ni Bimetallic Catalysts Assembled on Diatomite.
ACS Appl Mater Interfaces
November 2024
Hunan Key Lab of Mineral Materials and Application, Department of Inorganic Materials, School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, P. R. China.
There exists an imperative exigency to ascertain catalysts of cost-effectiveness and energy efficiency for the facilitation of industrial CO methanation. In this area, the dual metal synergistic enhancement of the metal-support interaction emerges as a highly promising strategy. Here, Diatomite (Dt) was used as the support, and a series of CoyNi/Dt (Co as the first component and Ni as the second component) composite catalysts were constructed using an ultrasound-assisted coimpregnation method.
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