Polyostotic fibrous dysplasia, a major osseous change in McCune-Albright syndrome, is seen in the cranium, facial bones, bones of the extremities, and ribs, but rarely in the spine. Spinal X-rays revealed no abnormalities in an 8-year-old girl with this syndrome, but 99mTc-methylene diphosphonate bone scintigraphy disclosed high-density areas in the thoracic and lumbar vertebrae. Multiple well-circumscribed areas of low signal intensity were seen on T1-weighted magnetic resonance imaging (MRI) of the spine. Although MRI spine scans in this disease have never been reported, our findings in this case proved interesting for evaluating osseous lesions. MRI made it possible to differentiate between fibrous lesions (low signal intensity on T1- and T2-weighted MRI) and cartilaginous lesions (low signal intensity on T1-weighted MRI and high signal intensity on T2-weighted MRI).

Download full-text PDF

Source
http://dx.doi.org/10.1007/BF02020213DOI Listing

Publication Analysis

Top Keywords

signal intensity
16
low signal
12
magnetic resonance
8
resonance imaging
8
mccune-albright syndrome
8
intensity t1-weighted
8
mri spine
8
lesions low
8
t2-weighted mri
8
mri
6

Similar Publications

Lesion Location and Possible Etiology of Acute Unilateral Vestibulopathy.

Int J Gen Med

January 2025

Department of Neurology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, 100049, People's Republic of China.

Objective: Acute unilateral vestibulopathy (AUVP) is quite common in clinical practice, but lesion localization and etiological diagnosis of AUVP remain the current clinical challenges, and have always been the focus for researchers. The study aimed to explore the lesion site and possible etiology of AUVP.

Methods: This study is a retrospective study.

View Article and Find Full Text PDF

Background: Pimavanserin is a new non-dopamine neurotransmitter antipsychotic drug. This study aimed to conduct a post-marketing pharmacovigilance study of pimavanserin, through data mining technology using the FDA Adverse Event Reporting System (FAERS) database.

Research Design And Methods: We analyzed adverse event reports for patients using pimavanserin.

View Article and Find Full Text PDF

With enrichment of tetracycline (TC) in ecosystems, its accurate detection has become a major concern. Noble-metal nano-particles have attracted great interest as potential materials for sensing applications because of their remarkable electrical properties and adaptability. Herein, a novel electro-chemical detection technique based on carbon nano-tubes (CNTs) as the support material is developed to detect TC with high precision.

View Article and Find Full Text PDF

Upon exposure to salt stress, calcium signaling in plants activates various stress-responsive genes and proteins along with enhancement in antioxidant defense to eventually regulate the cellular homeostasis for reducing cytosolic sodium levels. The coordination among the calcium signaling molecules and transporters plays a crucial role in salinity tolerance. In the present study, twenty-one diverse indigenous rice genotypes were evaluated for salt tolerance during the early seedling stage, and out of that nine genotypes were further selected for physio-biochemical study.

View Article and Find Full Text PDF

Background: Acute pain management is critical in postoperative care, especially in vulnerable patient populations that may be unable to self-report pain levels effectively. Current methods of pain assessment often rely on subjective patient reports or behavioral pain observation tools, which can lead to inconsistencies in pain management. Multimodal pain assessment, integrating physiological and behavioral data, presents an opportunity to create more objective and accurate pain measurement systems.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!