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JBJS Case Connect
January 2025
Cedars Sinai Medical Center, Los Angeles, California.
Case: A 14-year-old male athlete presented with a 9-month history of low back pain, worse with hyperextension. Nonoperative management for bilateral L4 spondylolysis had been unsuccessful. The patient underwent a novel magnetic resonance imaging (MRI) that generated a synthetic computed tomography (sCT).
View Article and Find Full Text PDFJBJS Case Connect
January 2025
Department of Surgery, The Aga Khan University, Karachi, Pakistan.
Case: Thirty-five-year-old man presented with 14 cm segmental tibial defect after crush injury (Gustilo Anderson type-IIIA). Tetrafocal bone transport using Ilizarov frame was performed with 3 osteotomies. Two minor complications-skin invagination and failure at proximal docking site-were addressed.
View Article and Find Full Text PDFCureus
December 2024
Anesthesiology, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Bone marrow aspiration is an essential procedure for diagnosing hematological conditions and therapeutic applications, such as bone marrow aspirate concentrate (BMAC) therapy for non-union of bones. This report presents a case of a 35-year-old male with femoral non-union treated with BMAC, requiring the collection of a large bone marrow aspirate volume. A novel, low-cost modification to the standard bone marrow aspiration apparatus was developed using components from an intravenous (IV) drip set, including a rubber bulb connector and a luer lock connector.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Mechanical Engineering, Centre for Mechanical Technology & Automation (TEMA), University of Aveiro, Aveiro, 3810-193, Portugal.
Background: Bone fractures represent a global public health issue. Over the past few decades, a sustained increase in the number of incidents and prevalent cases have been reported, as well as in the years lived with disability. Current monitoring techniques predominantly rely on imaging methods, which can result in subjective assessments, and expose patients to unnecessary cumulative doses of radiation.
View Article and Find Full Text PDFAdv Exp Med Biol
January 2025
Department of Stem Cells & Regenerative Medicine, Centre for Interdisciplinary Research, D Y Patil Education Society (Deemed to be University), Kolhapur, India.
Bone tissue engineering is a promising field that aims to rebuild the bone tissue using biomaterials, cells, and signaling molecules. Materials like natural and synthetic polymers, inorganic materials, and composite materials are used to create scaffolds that mimic the hierarchical microstructure of bone. Stem cells, particularly mesenchymal stem cells (MSCs), play a crucial role in bone tissue engineering by promoting tissue regeneration and modulating the immune response.
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