Background: Edema often occurs in association with venous leg ulcers.
Objective: Our purpose was to assess lymphatic function in the legs of patients with venous leg ulcers.
Methods: Quantitative lymphoscintigraphy was performed in 22 normal control subjects, 32 patients with venous leg ulcers, and 7 patients with varicose veins only.
Results: Lymph drainage declined with age in the normal controls (r = -0.57; p = 0.0001). Lymphatic function was reduced in the ulcerated legs compared with normal limbs (age < 65 years; p < 0.0001) and in edematous legs compared with nonedematous legs (age > 65 years; ulcerated legs, p = 0.016; nonulcerated legs, p = 0.021). Lymph drainage was lower in the legs of patients with varicose veins only (p = 0.004).
Conclusion: Impaired lymphatic function is associated with both venous leg ulcers and chronic venous hypertension.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0190-9622(93)70078-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Simultaneous pancreas-kidney (SPK) transplantation is a recognized treatment for patients with insulin-dependent diabetes and advanced chronic kidney disease or end-stage renal disease (ESRD), offering significant survival benefits. However, it is associated with a higher risk of venous thrombosis, which can jeopardize the survival of the pancreaticoduodenal graft. This case report describes a patient with type 2 diabetes, hypertension, and ESRD who developed acute, occlusive deep vein thrombosis (DVT) involving the right common femoral, profunda femoral, and greater saphenous veins on postoperative day 1 (POD1) following a deceased donor SPK transplant, despite systemic prophylactic anticoagulation.
View Article and Find Full Text PDFThe effect of calf muscular vein thrombosis on the prognosis within one year postoperatively of geriatric hip fracture patients: a propensity score-matched analysis.
BMC Geriatr
December 2024
Department of Orthopedic Surgery, West China Hospital, Orthopedic Research Institute, Sichuan University, Chengdu, Sichuan, China.
Introduction: Calf muscular vein thrombosis (CMVT) is a type of distal deep vein thrombosis, which is common in geriatric hip fracture patients. However, studies focusing on whether the orthopedic operation has an impact on the prognosis of geriatric hip fracture patients with CMVT are very limited. Therefore, the aim of this study was to explore whether geriatric hip fractures with CMVT affect the mortality of patients within one year postoperatively.
View Article and Find Full Text PDFBone and Joint Involvement in Beta Thalassemic Patients: A Cross-sectional Study.
Indian J Orthop
January 2025
Dayanand Medical College and Hospital, Tagore Nagar, civil lines, Ludhiana, Punjab 141001 India.
Purpose: There is paucity of guidelines with inadequate data available about the extent and prevention of bone and joint disease in beta-thalassemic patients in Indian population. This study aims to determine bone and joint involvement in beta-thalassemic patients. It evaluates serum biochemical parameters of bone formation and resorption and correlates with the symptomatology in these patients.
View Article and Find Full Text PDFThis case report describes a unique presentation of May-Thurner syndrome (MTS) in a 28-year-old woman, characterized by the congenital bifurcation of the left common iliac vein (LCIV) into the outer (OLCIV) and inner (ILCIV) segments. Both veins experienced significant compression - OLCIV proximally and ILCIV medially - due to the overlying right common iliac artery (RCIA) and lumbar spine. The patient presented with bilateral spider veins, lower extremity swelling, pelvic discomfort, and bilateral leg cramping.
View Article and Find Full Text PDFExtensive Deep Vein Thrombosis in a Young Man Taking Tirzepatide for Weight Loss.
AACE Clin Case Rep
September 2024
Department of Internal Medicine, College of Medicine & Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Background/objective: Obesity and rapid weight loss are risk factors for developing deep vein thromboses (DVTs). Our aims were to present a patient who developed extensive DVT after relatively rapid and severe weight loss that followed taking tirzepatide and to raise the awareness among health care professionals regarding the risk of DVT that can be associated with significant weight loss due to these agents.
Case Report: We present the case of a 20-year-old young man, with raised body mass index of >35 kg/m, who was initiated on tirzepatide treatment for weight loss, with 12-kg weight lost over 6 weeks.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!