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Acute Cholecystitis and Fetal Loss Due to in Early Pregnancy.
J Glob Infect Dis
December 2024
Department of General Medicine, Sultan Qaboos Hospital, Salalah, Oman.
Executioner caspases degrade essential mediators of pathogen-host interactions to inhibit growth of intracellular Listeria monocytogenes.
Cell Death Dis
January 2025
Faculty of Science and Medicine, Department of Oncology, Microbiology and Immunology, Anatomy unit, University of Fribourg, CH-1700, Fribourg, Switzerland.
Cell death mediated by executioner caspases is essential during organ development and for organismal homeostasis. The mechanistic role of activated executioner caspases in antibacterial defense during infections with intracellular bacteria, such as Listeria monocytogenes, remains elusive. Cell death upon intracellular bacterial infections is considered altruistic to deprive the pathogens of their protective niche.
View Article and Find Full Text PDFDevelopment of a colloidal gold immunochromatographic assay utilizing dual-antibody sandwich method for detecting .
Front Microbiol
January 2025
College Food Science and Light Industry, Nanjing Tech University, Nanjing, China.
A colloidal gold immunochromatographic assay (ICA) based on a dual-antibody sandwich method was developed for the rapid and convenient detection of () antigens in the early stages of infection. Monoclonal antibodies designed as 5B3 targeting the conserved region of 56 kDa outer membrane protein in various strains of were generated through cell fusion and screening techniques and combined with previously prepared polyclonal antibodies as detection antibodies to establish the ICA. Colloidal gold and polyclonal antibody-colloidal gold complexes were synthesized under optimized conditions.
View Article and Find Full Text PDFFormulation and biological evaluation of sodium alginate-based films blended with watercress oil: A Promising solution for combating foodborne pathogens and potential food packaging applications.
Food Chem
January 2025
Department of Chemistry, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia. Electronic address:
The main objective of this study is to prepare sodium alginate (SA)-based biofilms incorporated with watercress oil (WCO) as an antimicrobial material for sustainable food packaging. The physicochemical, antioxidant, and antibacterial properties of the prepared bio-based films were investigated. The antioxidant activity showed a remarkable increase, with DPPH inhibition increasing from 13.
View Article and Find Full Text PDFInnovative Applications of Bacteria and Their Derivatives in Targeted Tumor Therapy.
ACS Nano
January 2025
Institute of Nanobiomaterials and Immunology & Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, School of Life Sciences, Taizhou University, Zhejiang Taizhou 318000, China.
Despite significant progress in cancer treatment, traditional therapies still face considerable challenges, including poor targeting, severe toxic side effects, and the development of resistance. Recent advances in biotechnology have revealed the potential of bacteria and their derivatives as drug delivery systems for tumor therapy by leveraging their biological properties. Engineered bacteria, including , , and , along with their derivatives─outer membrane vesicles (OMVs), bacterial ghosts (BGs), and bacterial spores (BSPs)─can be loaded with a variety of antitumor agents, enabling precise targeting and sustained drug release within the tumor microenvironment (TME).
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