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Actionable Gene Alterations Identified in Patients With Malignant Melanoma by Targeted Sequencing in Japan.
JCO Precis Oncol
January 2025
Department of Medical Oncology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.
Purpose: Precision medicine plays an important role in the treatment of patients with advanced melanoma. Despite its high incidence in White patients, advanced melanoma is rare in Asian countries, hampering prospective clinical trials targeting the Asian population. This retrospective study aimed to elucidate the real-world molecular diagnoses and outcomes of Japanese patients with melanoma using comprehensive genome profiling (CGP).
View Article and Find Full Text PDFEffects of the Affordable Care Act on Contraception, Pregnancy, and Pregnancy Termination Rates.
Obstet Gynecol
February 2025
Department of Cardiology, the Department of Obstetrics and Gynecology, and the Division of Research, Kaiser Permanente Northern California, and Graduate Medical Education, Kaiser Permanente Oakland Medical Center, Oakland, and the Division of Research, Kaiser Permanente, Pleasanton, California.
Objective: To investigate the effects of the Affordable Care Act (ACA) and its elimination of cost sharing on contraception utilization, pregnancy rates, and abortion rates.
Methods: We conducted a retrospective cohort study within a health care system serving more than 4.5 million insured members across 21 medical centers and 250 clinics.
Artificial Intelligence Scribe and Large Language Model Technology in Healthcare Documentation: Advantages, Limitations, and Recommendations.
Plast Reconstr Surg Glob Open
January 2025
Department of Computer Science, Johns Hopkins University, Baltimore, MD.
Artificial intelligence (AI) scribe applications in the healthcare community are in the early adoption phase and offer unprecedented efficiency for medical documentation. They typically use an application programming interface with a large language model (LLM), for example, generative pretrained transformer 4. They use automatic speech recognition on the physician-patient interaction, generating a full medical note for the encounter, together with a draft follow-up e-mail for the patient and, often, recommendations, all within seconds or minutes.
View Article and Find Full Text PDFDigital healthcare services in community pharmacies in Switzerland: Pharmacist and patient acceptability, and pharmacist readiness-the Pneumoscope™ pilot study.
Digit Health
January 2025
School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
Background: The integration of artificial intelligence (AI)-based pharmaceutical services in community pharmacy (CP) settings has the potential to enhance point-of-care services and improve informed patient access to healthcare. The Pneumoscope™, an innovative AI-powered digital stethoscope that analyses lung sounds to detect specific respiratory pathologies, could be a valuable tool for pharmacists in conducting respiratory screening. To understand how this device can be implemented in the healthcare system, this exploratory research aims to assess the acceptability of pharmacists and patients, and the pharmacists' readiness to use the Pneumoscope™ in CPs for respiratory disease management.
View Article and Find Full Text PDFMedicaid Expansion and Survival Outcomes Among Men With Prostate Cancer.
Cureus
January 2025
Clive O. Callender Outcomes Research Center, Howard University College of Medicine, Washington, D.C., USA.
Introduction: Prostate cancer stands as one of the most diagnosed malignancies among men worldwide. With the recent expansion of Medicaid under the Affordable Care Act (ACA), millions more Americans now have health insurance coverage, potentially influencing healthcare access and subsequent outcomes for various illnesses, including prostate cancer. Yet, the direct correlation between Medicaid expansion and cancer-specific survival among individuals with prostate cancer remains an area warranting comprehensive exploration.
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