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Paraneoplastic Cerebellar Degeneration Leading to an Early Diagnosis of Peritoneal Serous Papillary Carcinoma.
Intern Med
October 2024
Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
Article Synopsis
- A 77-year-old woman with worsening coordination issues and anti-Yo antibodies was suspected of having paraneoplastic cerebellar degeneration (PCD).
- After examining her for cancer, doctors found and removed a mass in the Douglas fossa, later identified as stage IIB peritoneal serous papillary carcinoma (PSPC), which is challenging to detect early.
- The PCD was treated with intravenous immunoglobulin (IVIG), highlighting the need for early diagnosis and treatment of PSPC as a possible cause of PCD linked to anti-Yo antibodies.
Assessment of oncological safety and utility of hysteroscopy in high grade endometrial cancers: Results from an Israel gynecologic oncology group study.
Eur J Obstet Gynecol Reprod Biol
February 2024
Barzilai University Medical Center, Ashkelon, Israel; Faculty of Health Sciences, Ben-Gurion University of Negev, Beer-Sheva, Israel.
Objective: To compare survival measures of women with Stage I high-grade endometrial cancer who underwent either hysteroscopy or a non-hysteroscopic procedure as a diagnostic procedure.
Study Design: 298 patients with stage I high grade endometrial cancer who underwent surgery between 2002 and 2014. Patients were divided into two groups: hysteroscopy and non-hysteroscopy (curettage or office endometrial biopsy).
Factor affecting lymph node metastasis in uterine papillary serous carcinomas: a retrospective analysis.
J Obstet Gynaecol
November 2022
Department of Gynecologic Oncology, Faculty of Medicine, Ankara City Hospital, University of Health Sciences, Ankara, Turkey.
The aim of this study was to investigate the risk factors for lymph node metastasis (LNM) in patients with uterine serous cancer (USC) who underwent systematic staging surgery. Eighty patients who were operated on for pure uterine serous papillary carcinoma between 2008 and 2020 in our clinic were retrospectively analysed. The effects of demographic information and clinicohistopathological characteristics of the included patients on LNM were examined.
View Article and Find Full Text PDFHigh gene expression predicts response to chemotherapy and prognosis of high-grade serous ovarian cancer patients.
J Int Med Res
November 2022
Department of Intensive Care Unit, Hebei Medical University, Fourth Hospital, Shijiazhuang, China.
Article Synopsis
- High-grade serous ovarian cancer (HGSOC) is a severe form of cancer linked to aberrant differentiation, with homeobox protein A9 (HoxA9) playing a key role in this process.
- The study used quantitative PCR and immunohistochemistry to analyze mRNA and protein levels of HoxA9, finding that increased expression levels correlated with chemotherapy resistance and worse clinical outcomes.
- The findings suggest that high HoxA9 expression serves as an independent prognostic indicator for poor survival in HGSOC patients, potentially guiding future treatment strategies.
Prognostic significance of pretreatment thrombocytosis in endometrial cancer: an Israeli Gynecologic Oncology Group study.
Int J Gynecol Cancer
November 2021
Edith Wolfson Medical Center, Holon, Israel.
Objective: Endometrial cancer prognosis is related to stage, histology, myometrial invasion, and lymphovascular space invasion. Several studies have examined the association between pretreatment thrombocytosis and patient outcomes with contrasting results regarding prognosis. Our aim was to evaluate the association of pretreatment platelet count with outcomes in endometrial cancer patients.
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