In Europe only a few cases of infantile botulism have been identified. A two month old infant fell ill with feeding difficulties and profound general weakness. Clostridium botulinum and botulinal toxin, the causative agents, were isolated from the patients stool. We describe the typical clinical symptoms and the investigations confirming the diagnosis.
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An 8-month old girl, weighing 9 kg, was brought by her parents at 8.15 am to the Emergency Department (ED) for a progressive worsening of weakness and acute respiratory failure. On admission, the baby presented with poor oral intake, a weak cry and extremely weak muscular body control.
View Article and Find Full Text PDF[Botulism in infancy - survey of literature based on a case report].
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Article Synopsis
- The article discusses the challenges of diagnosing infant botulism, particularly in a six-month-old baby where it presented alongside food-borne botulism.
- The authors emphasize the importance of thorough patient history and clinical examination for diagnosis, and highlight the need for microbiological and electrophysiological tests to confirm the disease.
- They also address the complexities of treatment and the urgency of preventing this rare but dangerous disease through better nutritional hygiene practices.
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Laboratory of Clinical and Environmental Teratology, Room 308. R/A, Alfred I. duPont Hospital for Children, Box 269, Thomas Jefferson University, Wilmington, DE 19899, USA.
Establishing successful vaccine programs for pregnant women would be the quintessence of preventive medicine when you realize the preventive potential for reproductive problems of many of the new and old vaccines. The development of vaccines to prevent maternal, fetal and newborn disease is actually in its infancy. The risks and benefits are discussed in detail as well as the most appropriate and inappropriate time to immunize women of reproductive age and pregnant women.
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J Paediatr Child Health
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Pediatrics Department, University Hospital of Los Andes and National Institute of Research and Studies of Infancy, Mérida, Venezuela.
A 3-month-old male infant was admitted to the University Hospital of Los Andes with a history of constipation, weak crying, poor feeding, flaccidity and later bilateral ptosis and hyporeflexia. The admission diagnosis was septicaemia until an electrophysiological study reported postetanic facilitation with 50 Hz/seg stimulations four days later. The Clostridium botulinum toxin type B was isolated from the infant's stool samples and the organism grew in anaerobic cultures.
View Article and Find Full Text PDFAccording to international references the publication ascertains the etiologic role of neurotoxin producing Clostridial spp., other than C. botulinum in Infant botulism.
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