The inhibitory effect of cyclophosphamide hydrolysis product (CPHP) on vitamin B12 binding ability to proteins has been established. The ester N-(2-chloroethyl)-N'-(3-phosphopropyl)-ethylenediamine hydrochloride is probably responsible, in vitro, for blocking the protein binding sites. Preincubation of proteins with vitamin B12 prevents the inhibitory effect of CPHP.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1600-0773.1993.tb01333.x | DOI Listing |
Publication Analysis
Top Keywords
vitamin b12
12
b12 binding
8
hydrolysis product
8
inhibition vitamin
4
binding capacity
4
capacity proteins
4
proteins hydrolysis
4
product cyclophosphamide
4
cyclophosphamide inhibitory
4
inhibitory cyclophosphamide
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!