Objective: To characterize the epidemiology of polymicrobial bacteremia (PMB) among critically ill patients.
Design: Prospective clinical study.
Setting: University medical center.
Patients: All patients with positive blood cultures in a medical-surgical ICU.
Measurements: PMB represents 8.4% of all true bacteremia in our ICU. Most of these patients were postoperative but none had malignancies or significant immunodepression. Over three-quarters of the episodes were nosocomial. No significant differences in factors associated with PMB were found when they were compared with a cohort of 154 monomicrobial episodes. Enterobacteriaceae were the most common organisms. Intravascular devices (42.8%) were the most common source of PMB, followed by intra-abdominal origin (21.4%). The overall mortality was 7.1%, a lower rate than has previously been described.
Conclusions: We suggest catheter replacement in patients who develop PMB and improving techniques of catheter maintenance in order to reduce its incidence.
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http://dx.doi.org/10.1007/BF01709273 | DOI Listing |
Infect Drug Resist
January 2025
Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, People's Republic of China.
Objective: This study aimed to analyze the antimicrobial resistance profiles, clinical characteristics and risk factors of bacteremia caused by complex (ECC) strains.
Methods: We retrospectively collected clinical data from patients diagnosed with ECC bacteremia between 2013 and 2022 in a tertiary hospital in Jiangsu. Subgroup analyses were performed based on multidrug resistance (MDR), nosocomial acquisition, polymicrobial bacteremia, and mortality.
J Infect Chemother
January 2025
Department of Clinical Laboratory, Kanazawa Medical University Hospital, 1-1 Daigaku, Uchinada, Kahoku, Ishikawa 920-0293, Japan; Department of Infectious Diseases, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Kahoku, Ishikawa, 920-0293, Japan. Electronic address:
A 70-year-old woman with a 6-month history of poor hygiene presented with a right occipital mass, ulceration, and neck swelling. The right occipital region was infested with approximately 100 fly maggots, and the mass contained a foul-smelling abscess. Maggots were removed, and the mass was drained, irrigated, and dressed with padding.
View Article and Find Full Text PDFNagoya J Med Sci
November 2024
Department of Clinical Infectious Diseases, Aichi Medical University, Nagakute, Japan.
() is known to cause intra-abdominal and anaerobic bloodstream infections. However, clinical insights and information on antimicrobial susceptibility in infections are limited. This study aimed to elucidate the clinical characteristics and antimicrobial susceptibility of infections.
View Article and Find Full Text PDFMicroorganisms
December 2024
Department of Infectious Disease, Chonnam National University Hwasun Hospital, Hwasun 58128, Republic of Korea.
The risk factors and outcomes associated with persistent bacteremia are not well-defined. This retrospective cohort study analyzed 214 cases of bacteremia diagnosed between 2005 and 2022 at two university hospitals, focusing on the clinical and microbiologic characteristics and outcomes of persistent bacteremia. Persistent bacteremia, defined as the detection of for ≥5 days after the initial blood culture, occurred in 25.
View Article and Find Full Text PDFCureus
November 2024
Pulmonary and Critical Care Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
We present a case of bacteremia in the setting of polymicrobial osteomyelitis. is a Gram-variable bacterium that has been rarely documented as the etiologic organism in human infections such as septic arthritis or otitis media, and even more rarely reported as an organism associated with bacteremia. The patient presented with septic shock and the physical exam was notable for gangrene of bilateral feet.
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