Forty-five patients suffering from systemic lupus erythematosus were studied in respect of their serologically defined HLA antigens. HLA-B8 antigen was found in 37-8% of patients as compared to 22% of controls. Individuals carrying the HLA-B8 antigen have a 2-15 times greater risk of developing systemic lupus erythematosus than those not carrying this antigen.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1006636PMC
http://dx.doi.org/10.1136/ard.36.1.83DOI Listing

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