A case of breast carcinoma with neuroendocrine features occurring in an elderly male patient is reported. Histologically, the tumor was characterized by solid growth with nests and ribbons of small to medium-size uniform neoplastic cells. Argyrophilia, expression of chromogranins at both protein and gene level, and the presence of dense granules of the neurosecretory type by electron microscopy were demonstrated.
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http://dx.doi.org/10.3109/01913129309015404 | DOI Listing |
Psychiatry Clin Neurosci
December 2022
Department of Psychiatry, Nagoya University Graduate School of Medicine, Aichi, Japan.
Senile depression (SD) is a heterogeneous syndrome. Several clinical profiles are more likely to appear in SD than in early-life depression, but it remains unclear whether the pathophysiology is different. The prevalence of dementia increases with aging, and the underlying pathophysiological processes in the preclinical phase begin even before cognitive deficits or neurological signs appear.
View Article and Find Full Text PDFMicrosc Res Tech
October 2022
Department of Cell and Tissues, Faculty of Veterinary Medicine, Assiut University, Asyut, Egypt.
The vagina is part of the genitalia and constitutes part of the birth canal. Sperm is deposited into vagina, and it acts in transport of sperm. Pregnancy is a complex process involving different physiological changes in the body associated with hormonal and metabolic alterations that control maternal and fetal demands.
View Article and Find Full Text PDFInt J Surg Case Rep
December 2021
Department of Hepatobiliary Surgery, Hebei General Hospital, Shijiazhuang 050051, Hebei Province, China. Electronic address:
Introduction And Importance: To describe an unusual case with a primary hepatic neuroendocrine tumour (PHNET) with multiple liver metastases.
Case Presentation: We reported a 65-year-old woman with PHNET with multiple liver metastases. She was highly suspected of having primary liver cancer with multiple intrahepatic metastases before liver biopsy, but was diagnosed with PHNET with multiple liver metastases after histopathology and immunohistochemistry (IHC) examinations.
Anat Rec (Hoboken)
August 2019
Unit of Histology and Veterinary Pathology, Institute for Animal Health, Veterinary College, University of Las Palmas de Gran Canaria, Campus Universitario Cardones, Las Palmas, Spain.
Merkel cells (MCs) are neuroendocrine cells involved with tactile sense, growth, differentiation, and homeostasis of the skin as well as in different cutaneous diseases. Specific staining techniques are required for their identification because they are not easily visible in paraffin sections stained with hematoxylin and eosin. The present study assess the histochemical features of the MCs in dogs comparing with those described for other mammals in the literature and with the use of immunohistochemistry.
View Article and Find Full Text PDFJ Vet Diagn Invest
May 2017
Department of Veterinary Pathology, School of Veterinary Medicine (Michishita, Takagi, Kishimoto, Nakahira, Nogami, Takahashi), Nippon Veterinary and Life Science University, Tokyo, Japan.
A 35-mo-old spayed female mixed-breed cat with continuous vomiting, emaciation, and abdominal distention for 2 wk was presented to a private veterinary clinic for evaluation. At 71 d after the initial visit, the cat died with anemia, jaundice, and hypoalbuminemia, and was subjected to autopsy. Grossly, numerous firm masses, 0.
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