Rabbit antisera to Leptospira interrogans, Borrelia hermsii, and Treponema phagedenis biotype Reiter, reactive to shared spirochetal antigens, failed to enhance phagocytosis of Treponema pallidum by macrophages, while immunoglobulin G to Treponema pallidum subsp. pertenue and Treponema paraluiscuniculi promoted phagocytosis. Opsonic antibodies are directed to pathogen-restricted, not shared spirochetal, antigens.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC302795PMC
http://dx.doi.org/10.1128/iai.61.2.781-784.1993DOI Listing

Publication Analysis

Top Keywords

treponema pallidum
12
shared spirochetal
8
spirochetal antigens
8
opsonization treponema
4
pallidum mediated
4
mediated immunoglobulin
4
immunoglobulin antibodies
4
antibodies induced
4
induced pathogenic
4
pathogenic treponemes
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!